PMID- 19590704
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20211020
IS  - 0912-0009 (Print)
IS  - 1880-5086 (Electronic)
IS  - 0912-0009 (Linking)
VI  - 45
IP  - 1
DP  - 2009 Jul
TI  - A rice bran oil diet improves lipid abnormalities and suppress hyperinsulinemic 
      responses in rats with streptozotocin/nicotinamide-induced type 2 diabetes.
PG  - 29-36
LID - 10.3164/jcbn.08-257 [doi]
AB  - The aim of this study was to determine the effects of rice bran oil (RBO) on 
      lipid metabolism and insulin resistance in rats with 
      streptozotocin/nicotinamide-induced type 2 diabetes mellitus (T2DM). Rats were 
      divided into two groups: the control group (15% soybean oil, contains 0 g 
      gamma-oryzanol and 0 g gamma-tocotrienol/150 g oil for 5 weeks) and the RBO group 
      (15% RBO, contains 5.25 g gamma-oryzanol and 0.9 g gamma-tocotrienol/150 g oil 
      for 5 weeks). Compared with the control group, the RBO group had a lower plasma 
      nonesterified fatty acid concentration, ratio of total to 
      high-density-lipoprotein cholesterol, hepatic cholesterol concentration, and area 
      under the curve for insulin. The RBO group had a higher high-density-lipoprotein 
      cholesterol concentration and greater excretion of fecal neutral sterols and bile 
      acid than did the control group. RBO may improve lipid abnormalities, reduce the 
      atherogenic index, and suppress the hyperinsulinemic response in rats with 
      streptozotocin/nicotinamide-induced T2DM. In addition, RBO can lead to increased 
      fecal neutral sterol and bile acid excretion.
FAU - Chou, Tsui-Wei
AU  - Chou TW
AD  - Department of Tourism and Hospitality Management, Kainan University, Taoyuan 
      33857, Taiwan.
FAU - Ma, Chien-Ya
AU  - Ma CY
FAU - Cheng, Hsing-Hsien
AU  - Cheng HH
FAU - Chen, Ya-Yen
AU  - Chen YY
FAU - Lai, Ming-Hoang
AU  - Lai MH
LA  - eng
PT  - Journal Article
DEP - 20090630
PL  - Japan
TA  - J Clin Biochem Nutr
JT  - Journal of clinical biochemistry and nutrition
JID - 8700907
PMC - PMC2704324
OTO - NOTNLM
OT  - insulin resistance
OT  - rice bran oil
OT  - type 2 diabetes
OT  - gamma-oryzanol
OT  - gamma-tocotrienol
EDAT- 2009/07/11 09:00
MHDA- 2009/07/11 09:01
PMCR- 2009/07/01
CRDT- 2009/07/11 09:00
PHST- 2008/11/27 00:00 [received]
PHST- 2008/12/17 00:00 [accepted]
PHST- 2009/07/11 09:00 [entrez]
PHST- 2009/07/11 09:00 [pubmed]
PHST- 2009/07/11 09:01 [medline]
PHST- 2009/07/01 00:00 [pmc-release]
AID - jcbn08-257 [pii]
AID - 10.3164/jcbn.08-257 [doi]
PST - ppublish
SO  - J Clin Biochem Nutr. 2009 Jul;45(1):29-36. doi: 10.3164/jcbn.08-257. Epub 2009 
      Jun 30.