PMID- 19594087
OWN - NLM
STAT- MEDLINE
DCOM- 20090730
LR  - 20220330
IS  - 0001-5164 (Print)
IS  - 0001-5164 (Linking)
VI  - 60
IP  - 2
DP  - 2009
TI  - Effects of oral preoperative carbohydrate on early postoperative outcome after 
      thyroidectomy.
PG  - 67-73
AB  - BACKGROUND: Preoperative carbohydrate (CHO) reduces perioperative insulin 
      resistance and improves preoperative patient comfort. We tested the hypotheses 
      that preoperative CHO reduces the risk of postoperative nausea and vomiting 
      (PONV) and improves early postoperative patient comfort. METHODS: Two hundred 
      women scheduled for thyroidectomy were randomly allocated to drink 50 g CHO in 
      400 ml of water or 0.5 g aspartam in 100 ml of water 2 h before surgery. The 
      incidence and the severity of PONV, pain scores, and analgesic consumption were 
      recorded postoperatively. Intensity of thirst, hunger, anxiety, fatigue were 
      recorded on 100-mm visual analog scales just before the induction of anesthesia, 
      2, 6, and 24 h postoperatively. RESULTS: The incidence and severity of PONV were 
      similar in both groups. Patients from the CHO group reported significantly less 
      thirst (P = 0.007), hunger (P = 0.04), and fatigue (P = 0.01) than patients from 
      the control group. Postoperative pain scores did not differ significantly between 
      both groups (P = 0.34). However patients from the CHO group requested less 
      acetaminophen during the first 24 postoperative h: 3 g vs. 2 g (median, P = 
      0.002). CONCLUSIONS: Oral carbohydrate before thyroidectomy improves pre- and 
      postoperative patient comfort, as well as postoperative analgesia, but has no 
      effect on the PONV.
FAU - Lauwick, S M
AU  - Lauwick SM
AD  - Department of Anesthesia and Intensive Care Medicine, CHU de Liege, University of 
      Liege, Domaine du Sart Tilman, Liege, Belgium.
FAU - Kaba, A
AU  - Kaba A
FAU - Maweja, S
AU  - Maweja S
FAU - Hamoir, E E
AU  - Hamoir EE
FAU - Joris, Jean L
AU  - Joris JL
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - Belgium
TA  - Acta Anaesthesiol Belg
JT  - Acta anaesthesiologica Belgica
JID - 0421022
RN  - 0 (Dietary Carbohydrates)
SB  - IM
MH  - Administration, Oral
MH  - Adult
MH  - Aged
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Double-Blind Method
MH  - Female
MH  - Humans
MH  - Middle Aged
MH  - Pain, Postoperative/drug therapy
MH  - Postoperative Nausea and Vomiting/*prevention & control
MH  - Preoperative Care
MH  - Prospective Studies
MH  - Thyroidectomy
EDAT- 2009/07/15 09:00
MHDA- 2009/07/31 09:00
CRDT- 2009/07/15 09:00
PHST- 2009/07/15 09:00 [entrez]
PHST- 2009/07/15 09:00 [pubmed]
PHST- 2009/07/31 09:00 [medline]
PST - ppublish
SO  - Acta Anaesthesiol Belg. 2009;60(2):67-73.