PMID- 19610302
OWN - NLM
STAT- MEDLINE
DCOM- 20090827
LR  - 20211020
IS  - 0094-2405 (Print)
IS  - 0094-2405 (Electronic)
IS  - 0094-2405 (Linking)
VI  - 36
IP  - 6
DP  - 2009 Jun
TI  - Temporal resolution improvement using PICCS in MDCT cardiac imaging.
PG  - 2130-5
AB  - The current paradigm for temporal resolution improvement is to add more 
      source-detector units and/or increase the gantry rotation speed. The purpose of 
      this article is to present an innovative alternative method to potentially 
      improve temporal resolution by approximately a factor of 2 for all MDCT scanners 
      without requiring hardware modification. The central enabling technology is a 
      most recently developed image reconstruction method: Prior image constrained 
      compressed sensing (PICCS). Using the method, cardiac CT images can be accurately 
      reconstructed using the projection data acquired in an angular range of about 120 
      degrees, which is roughly 50% of the standard short-scan angular range 
      (approximately 240 degrees for an MDCT scanner). As a result, the temporal 
      resolution of MDCT cardiac imaging can be universally improved by approximately a 
      factor of 2. In order to validate the proposed method, two in vivo animal 
      experiments were conducted using a state-of-the-art 64-slice CT scanner (GE 
      Healthcare, Waukesha, WI) at different gantry rotation times and different heart 
      rates. One animal was scanned at heart rate of 83 beats per minute (bpm) using 
      400 ms gantry rotation time and the second animal was scanned at 94 bpm using 350 
      ms gantry rotation time, respectively. Cardiac coronary CT imaging can be 
      successfully performed at high heart rates using a single-source MDCT scanner and 
      projection data from a single heart beat with gantry rotation times of 400 and 
      350 ms. Using the proposed PICCS method, the temporal resolution of cardiac CT 
      imaging can be effectively improved by approximately a factor of 2 without 
      modifying any scanner hardware. This potentially provides a new method for 
      single-source MDCT scanners to achieve reliable coronary CT imaging for patients 
      at higher heart rates than the current heart rate limit of 70 bpm without using 
      the well-known multisegment FBP reconstruction algorithm. This method also 
      enables dual-source MDCT scanner to achieve higher temporal resolution without 
      further hardware modifications.
FAU - Chen, Guang-Hong
AU  - Chen GH
AD  - Department of Medical Physics, University of Wisconsin-Madison, Madison, 
      Wisconsin 53705, USA. gchen7@wisc.edu
FAU - Tang, Jie
AU  - Tang J
FAU - Hsieh, Jiang
AU  - Hsieh J
LA  - eng
GR  - R01 EB005712/EB/NIBIB NIH HHS/United States
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Med Phys
JT  - Medical physics
JID - 0425746
SB  - IM
MH  - *Algorithms
MH  - Heart/*diagnostic imaging
MH  - Radiographic Image Enhancement/*methods
MH  - Radiographic Image Interpretation, Computer-Assisted/*methods
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Tomography, X-Ray Computed/*methods
PMC - PMC2832064
EDAT- 2009/07/21 09:00
MHDA- 2009/08/28 09:00
PMCR- 2010/06/01
CRDT- 2009/07/21 09:00
PHST- 2009/07/21 09:00 [entrez]
PHST- 2009/07/21 09:00 [pubmed]
PHST- 2009/08/28 09:00 [medline]
PHST- 2010/06/01 00:00 [pmc-release]
AID - 034906MPH [pii]
AID - 10.1118/1.3130018 [doi]
PST - ppublish
SO  - Med Phys. 2009 Jun;36(6):2130-5. doi: 10.1118/1.3130018.