PMID- 19610530
OWN - NLM
STAT- MEDLINE
DCOM- 20090820
LR  - 20161124
IS  - 1025-9589 (Print)
IS  - 1025-9589 (Linking)
VI  - 20
IP  - 3
DP  - 2008 Jul-Sep
TI  - Highly sensitive C-reactive protein concentration and angiographic 
      characteristics of coronary lesion.
PG  - 100-3
AB  - BACKGROUND: The role of inflammation in all stages of atherosclerotic disease is 
      increasingly recognized especially in last few years. The chronic inflammatory 
      process can develop to an acute clinical event by the induction of plaque rupture 
      and therefore cause acute coronary syndrome. Creactive protein is a strong 
      predictor of clinical outcome in coronary artery disease and inflammation has 
      been implicated in the process. We aimed to evaluate the relationship between 
      pre-procedural highly sensitive C-Reactive Protein (hs-CRP) and angiographic 
      features in patients with acute coronary syndrome. METHODS: In a cross-sectional 
      study, we examined 100 patients admitted with acute coronary syndrome and 
      assessed the relationship between preprocedural hs-CRP concentration and coronary 
      angiographic lesions. RESULTS: One hundred patients with acute coronary syndrome 
      were assessed. Some of the results were as follows: mean age 59.26 +/- 11.04, 64% 
      male and 36% female. 34% of patients had unstable angina, 43% had Non ST 
      elevation myocardial infarction (NSTEMI) and 23% had ST elevation myocardial 
      infarction (STEMI). The mean value of hs-CRP was 4.26 +/- 1.42 mg/dl with highest 
      values in patients eccentric/irregular lesion and patients having macroscopic 
      thrombus (p = 0.01). CONCLUSION: Among patients with acute coronary syndrome 
      increased levels of hs-CRP correlates with specific high risk coronary artery 
      lesions.
FAU - Irfan, Ghazala
AU  - Irfan G
AD  - Department of Cardiology, Liquat National Hospital, Karachi, Pakistan.
FAU - Ahmad, Mansoor
AU  - Ahmad M
LA  - eng
PT  - Journal Article
PL  - Pakistan
TA  - J Ayub Med Coll Abbottabad
JT  - Journal of Ayub Medical College, Abbottabad : JAMC
JID - 8910750
RN  - 0 (Biomarkers)
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
MH  - Biomarkers/metabolism
MH  - C-Reactive Protein/*metabolism
MH  - Chi-Square Distribution
MH  - *Coronary Angiography
MH  - Coronary Artery Disease/*diagnostic imaging/*metabolism
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Predictive Value of Tests
MH  - Risk Factors
EDAT- 2009/07/21 09:00
MHDA- 2009/08/21 09:00
CRDT- 2009/07/21 09:00
PHST- 2009/07/21 09:00 [entrez]
PHST- 2009/07/21 09:00 [pubmed]
PHST- 2009/08/21 09:00 [medline]
PST - ppublish
SO  - J Ayub Med Coll Abbottabad. 2008 Jul-Sep;20(3):100-3.