PMID- 19617867
OWN - NLM
STAT- MEDLINE
DCOM- 20100127
LR  - 20211020
IS  - 1537-4521 (Electronic)
IS  - 0148-5717 (Print)
IS  - 0148-5717 (Linking)
VI  - 36
IP  - 10
DP  - 2009 Oct
TI  - Herpes simplex virus type-2 seropositivity among ever married women in South and 
      north Vietnam: a population-based study.
PG  - 616-20
LID - 10.1097/OLQ.0b013e3181a8cde4 [doi]
AB  - OBJECTIVE: To investigate herpes simplex virus type-2 (HSV-2) seropositivity and 
      associated risk factors in Vietnamese women. METHODS: Cross-sectional study with 
      personal interviews and gynecological examinations among population-based samples 
      of ever married women, aged 15 to 69 years, living in Ho Chi Minh City (HCMC) and 
      Hanoi in 1997. Type-specific IgG antibodies against HSV-2 were detected using 
      HerpeSelect ELISA (Focus Diagnostics). Adjusted prevalence ratios were estimated 
      with log-binomial regression. RESULTS: HSV-2 seroprevalence was higher in 1106 
      women from HCMC (30.8%, 95% CI: 28.1-33.4, age-standardized to 2000 world 
      standard population) than in 1170 women from Hanoi (8.8%, 95% CI: 7.1-10.5). In 
      HCMC, HSV-2 seroprevalence was higher for women who were not married, HPV DNA 
      positive, current hormonal contraceptive users, or had a history of multiple 
      sexual partners or spontaneous abortion. HCMC seroprevalence was inversely 
      associated with educational attainment, age at first intercourse, and age at 
      first pregnancy. In the multivariable model for HCMC, a trend of increasing HSV-2 
      seroprevalence with age was observed, and prevalence ratios were nearly identical 
      to age-adjusted prevalence ratios for marital status, age at first pregnancy, and 
      HPV DNA positivity. CONCLUSIONS: HSV-2 was notably less prevalent in Hanoi than 
      HCMC, where it was associated with traditional HSV-2 risk factors. These results 
      are likely explained by socio-cultural, historical, economic, and demographic 
      factors related to urban-rural and regional differences. Future population-based 
      studies should include men and never-married women as a next step toward 
      obtaining a more nearly complete picture of HSV-2 epidemiology in Vietnam.
FAU - Le, Hoa Van
AU  - Le HV
AD  - Department of Epidemiology, University of North Carolina, Chapel Hill, North 
      Carolina 27599, USA.
FAU - Schoenbach, Victor J
AU  - Schoenbach VJ
FAU - Herrero, Rolando
AU  - Herrero R
FAU - Hoang Pham, Anh Thi
AU  - Hoang Pham AT
FAU - Nguyen, Hieu Trong
AU  - Nguyen HT
FAU - Nguyen, Thuy Thi
AU  - Nguyen TT
FAU - Munoz, Nubia
AU  - Munoz N
FAU - Franceschi, Silvia
AU  - Franceschi S
FAU - Vaccarella, Salvatore
AU  - Vaccarella S
FAU - Parkin, Max D
AU  - Parkin MD
FAU - Snijders, Peter J F
AU  - Snijders PJ
FAU - Morrow, Rhoda Ashley
AU  - Morrow RA
FAU - Smith, Jennifer S
AU  - Smith JS
LA  - eng
GR  - P01 AI030731-070003/AI/NIAID NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Sex Transm Dis
JT  - Sexually transmitted diseases
JID - 7705941
RN  - 0 (Antibodies, Viral)
RN  - 0 (Immunoglobulin G)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Antibodies, Viral/*blood
MH  - Cross-Sectional Studies
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Female
MH  - Herpes Genitalis/*epidemiology
MH  - Herpesvirus 2, Human/*immunology
MH  - Humans
MH  - Immunoglobulin G/blood
MH  - Middle Aged
MH  - Regression Analysis
MH  - Risk Factors
MH  - Seroepidemiologic Studies
MH  - Sexual Partners
MH  - Vietnam/epidemiology
PMC - PMC2901908
MID - NIHMS193543
EDAT- 2009/07/21 09:00
MHDA- 2010/01/28 06:00
PMCR- 2010/10/01
CRDT- 2009/07/21 09:00
PHST- 2009/07/21 09:00 [entrez]
PHST- 2009/07/21 09:00 [pubmed]
PHST- 2010/01/28 06:00 [medline]
PHST- 2010/10/01 00:00 [pmc-release]
AID - 10.1097/OLQ.0b013e3181a8cde4 [doi]
PST - ppublish
SO  - Sex Transm Dis. 2009 Oct;36(10):616-20. doi: 10.1097/OLQ.0b013e3181a8cde4.