PMID- 19619326 OWN - NLM STAT- MEDLINE DCOM- 20090914 LR - 20211020 IS - 1743-422X (Electronic) IS - 1743-422X (Linking) VI - 6 DP - 2009 Jul 20 TI - Challenging complications of treatment--human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin's disease: a case report. PG - 111 LID - 10.1186/1743-422X-6-111 [doi] AB - BACKGROUND: Reactivation of human herpesvirus 6 (HHV-6) occurs frequently in patients after allogeneic stem cell transplantation and is associated with bone-marrow suppression, enteritis, pneumonitis, pericarditis and also encephalitis. After autologous stem cell transplantation or intensive polychemotherapy HHV-6 reactivation is rarely reported. CASE REPORT: This case demonstrates a severe symptomatic HHV-6 infection with encephalitis and pneumonitis after autologous stem cell transplantation of a patient with relapsed Hodgkin's disease. CONCLUSION: Careful diagnostic work up in patients with severe complications after autologous stem cell transplantation is mandatory to identify uncommon infections. FAU - Bommer, Martin AU - Bommer M AD - Department of Internal Medicine III - Hematology/Oncology, University of Ulm, Ulm, Germany. martin.bommer@uniklinik-ulm.de FAU - Pauls, Sandra AU - Pauls S FAU - Greiner, Jochen AU - Greiner J LA - eng PT - Case Reports PT - Journal Article DEP - 20090720 PL - England TA - Virol J JT - Virology journal JID - 101231645 SB - IM MH - Adult MH - Encephalitis, Viral/*virology MH - Herpesvirus 6, Human/*isolation & purification MH - Hodgkin Disease/*complications/therapy MH - Humans MH - Male MH - Pneumonia/*virology MH - Roseolovirus Infections/*diagnosis/virology MH - Stem Cell Transplantation/*adverse effects PMC - PMC2718875 EDAT- 2009/07/22 09:00 MHDA- 2009/09/15 06:00 PMCR- 2009/07/20 CRDT- 2009/07/22 09:00 PHST- 2009/04/18 00:00 [received] PHST- 2009/07/20 00:00 [accepted] PHST- 2009/07/22 09:00 [entrez] PHST- 2009/07/22 09:00 [pubmed] PHST- 2009/09/15 06:00 [medline] PHST- 2009/07/20 00:00 [pmc-release] AID - 1743-422X-6-111 [pii] AID - 10.1186/1743-422X-6-111 [doi] PST - epublish SO - Virol J. 2009 Jul 20;6:111. doi: 10.1186/1743-422X-6-111.