PMID- 19626627
OWN - NLM
STAT- MEDLINE
DCOM- 20100217
LR  - 20091216
IS  - 1097-0339 (Electronic)
IS  - 1097-0339 (Linking)
VI  - 38
IP  - 1
DP  - 2010 Jan
TI  - Fine needle aspiration biopsy of renal mucinous tubular and spindle cell 
      carcinoma: report of two cases.
PG  - 51-5
LID - 10.1002/dc.21151 [doi]
AB  - Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare renal tumor. Here 
      we report two cases of MTSCC which were initially evaluated by fine needle 
      aspiration biopsy (FNAB) and followed by surgical resection of the tumors. The 
      cytomorphologic features of MTSCC were characterized by aggregates of relatively 
      uniform, predominantly oval to spindle cells intermixed with abundant 
      metachromatic myxoid matrix. Only rare epithelioid tumor cells with vacuolated 
      cytoplasm were present. Immunohistochemically, the tumor cells were positive for 
      CK7, CK19, CD10, vimentin, E-cadherin, alpha-methyl CoA racemase, and negative 
      for CK903 and CK20. EMA and carbonic anhydrase IX immunoreactivity was seen in 
      one of the two cases. Multiple chromosomal losses involving chromosomes 1, 2, 17 
      and likely chromosome 7 were revealed by fluorescence in situ hybridization 
      (FISH). These cytomorphologic, immunophenotypic, and cytogenetic features were 
      helpful for including this entity in the differential diagnosis of renal cell 
      carcinomas.
CI  - (c) 2009 Wiley-Liss, Inc.
FAU - Marks-Jones, Deborah A
AU  - Marks-Jones DA
AD  - Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, 
      Pennsylvania, USA.
FAU - Zynger, Debra L
AU  - Zynger DL
FAU - Parwani, Anil V
AU  - Parwani AV
FAU - Cai, Guoping
AU  - Cai G
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Diagn Cytopathol
JT  - Diagnostic cytopathology
JID - 8506895
SB  - IM
MH  - Biopsy, Fine-Needle
MH  - Carcinoma/diagnosis/*pathology
MH  - Chromosome Aberrations
MH  - Diagnosis, Differential
MH  - Humans
MH  - Immunophenotyping
MH  - In Situ Hybridization, Fluorescence
MH  - Kidney/*pathology
MH  - Kidney Neoplasms/diagnosis/*pathology
MH  - Male
MH  - Middle Aged
EDAT- 2009/07/25 09:00
MHDA- 2010/02/18 06:00
CRDT- 2009/07/24 09:00
PHST- 2009/07/24 09:00 [entrez]
PHST- 2009/07/25 09:00 [pubmed]
PHST- 2010/02/18 06:00 [medline]
AID - 10.1002/dc.21151 [doi]
PST - ppublish
SO  - Diagn Cytopathol. 2010 Jan;38(1):51-5. doi: 10.1002/dc.21151.