PMID- 19627764
OWN - NLM
STAT- MEDLINE
DCOM- 20110201
LR  - 20090724
IS  - 1579-2021 (Electronic)
IS  - 1575-0922 (Linking)
VI  - 56 Suppl 2
DP  - 2009 Apr
TI  - [Associated gastroenteropancreatic neuroendocrine tumours to familiar syndromes].
PG  - 10-5
LID - 10.1016/S1575-0922(09)70859-9 [doi]
AB  - Aproximately 5-10% of neuroendocrine tumours (NETs) of the gastroenteropancreatic 
      system (GEP) have an hereditary background. The known hereditary syndromes 
      include: multiple endocrine neoplasia type 1 (MEN 1), von Hippel Lindau disease 
      (VHL), neurofibromatosis type 1 (NF 1) and tuberous sclerosis complex (TSC). This 
      review discusses for each of these syndromes the: genes involved and specifics 
      types of mutations, disease prevalence, affected neuroendocrine tissues and 
      related clinical syndromes, and special morphological features of NETs on each of 
      these syndromes.
FAU - Lecumberri Pascual, Edurne
AU  - Lecumberri Pascual E
AD  - Servicio de Endocrinologia y Nutricion, Fundacion Jimenez Diaz Capio, Madrid, 
      Espana. edurnelecumberri@hotmail.com
LA  - spa
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - Tumores neuroendocrinos gastroenteropancreaticos asociados a sindromes 
      familiares.
DEP - 20090518
PL  - Spain
TA  - Endocrinol Nutr
JT  - Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y 
      Nutricion
JID - 100886482
RN  - Gastro-enteropancreatic neuroendocrine tumor
SB  - IM
MH  - Humans
MH  - Intestinal Neoplasms/genetics
MH  - Multiple Endocrine Neoplasia Type 1/genetics
MH  - Neoplasms, Multiple Primary/*genetics
MH  - Neoplastic Syndromes, Hereditary/*genetics
MH  - Neuroendocrine Tumors/genetics
MH  - Pancreatic Neoplasms/genetics
MH  - Stomach Neoplasms/genetics
EDAT- 2009/07/25 09:00
MHDA- 2011/02/02 06:00
CRDT- 2009/07/25 09:00
PHST- 2009/07/25 09:00 [entrez]
PHST- 2009/07/25 09:00 [pubmed]
PHST- 2011/02/02 06:00 [medline]
AID - S1575-0922(09)70859-9 [pii]
AID - 10.1016/S1575-0922(09)70859-9 [doi]
PST - ppublish
SO  - Endocrinol Nutr. 2009 Apr;56 Suppl 2:10-5. doi: 10.1016/S1575-0922(09)70859-9. 
      Epub 2009 May 18.