PMID- 19641362
OWN - NLM
STAT- MEDLINE
DCOM- 20091027
LR  - 20181201
IS  - 1423-0399 (Electronic)
IS  - 0042-1138 (Linking)
VI  - 83
IP  - 1
DP  - 2009
TI  - Effects of tamsulosin on lower urinary tract symptoms due to double-J stent: a 
      prospective study.
PG  - 66-9
LID - 10.1159/000224871 [doi]
AB  - OBJECTIVE: To evaluate the effect of tamsulosin in improving symptoms in, and 
      quality of life of, patients with indwelling double-J ureteral stents. PATIENTS 
      AND METHODS: This prospective study lasted from January 2005 to February 2007. 
      All the patients with symptomatic lower ureteral stones with <15 mm diameter were 
      enrolled in this prospective study, and were prospectively randomized (programs 
      Plus 1.0 and Plus 2.10; S-Plus, Taiwan) into two groups. There was a total of 146 
      patients with insertion of a double-J ureteral stent after ureteroscopic stone 
      removal. In group 1, 71 patients were enrolled and they received placebo for 2 
      weeks. Group 2 included 75 patients who received 0.4 mg of tamsulosin, once daily 
      for 2 weeks. All patients completed a 10-cm linear visual analogue scale (VAS) 
      for evaluating pain and voiding flank pain, and irritative domain of the 
      International Prostate Symptom Scale (IPSS) before double-J stent removal 2 weeks 
      later. RESULTS: The mean VAS for pain was 4.01 in group 1, 1.52 in group 2, and 
      for voiding flank pain it was 3.3 in group 1 and 1.93 in group 2. The mean score 
      of frequency in IPSS was 3.7 in group 1 and 1.55 in group 2. The mean score of 
      urgency in IPSS was 3.82 in group 1 and 1.43 in group 2. The mean score of 
      nocturia in IPSS was 2.01 in group 1 and 0.65 in group 2. The mean score of 
      quality of life in IPSS was 4.21 in group 1 and 1.6 in group 2. All p values are 
      <0.0001 with statistical significances. CONCLUSIONS: Tamsulosin improved a subset 
      of stent-related urinary symptoms, pain, voiding flank pain and quality of life.
CI  - Copyright 2009 S. Karger AG, Basel.
FAU - Wang, Chung-Jing
AU  - Wang CJ
AD  - Division of Urology, Department of Surgery, Saint Martin De Porres Hospital, 
      Chiayi, Taiwan, ROC.
FAU - Huang, Shi-Wei
AU  - Huang SW
FAU - Chang, Chien-Hsing
AU  - Chang CH
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20090727
PL  - Switzerland
TA  - Urol Int
JT  - Urologia internationalis
JID - 0417373
RN  - 0 (Adrenergic alpha-Antagonists)
RN  - 0 (Sulfonamides)
RN  - G3P28OML5I (Tamsulosin)
SB  - IM
MH  - Adrenergic alpha-Antagonists/*therapeutic use
MH  - Adult
MH  - Aged
MH  - Female
MH  - Flank Pain/drug therapy/etiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Quality of Life
MH  - Stents/*adverse effects
MH  - Sulfonamides/*therapeutic use
MH  - Tamsulosin
MH  - *Ureter
MH  - Ureteral Calculi/surgery
MH  - Urination Disorders/*drug therapy/etiology
EDAT- 2009/07/31 09:00
MHDA- 2009/10/29 06:00
CRDT- 2009/07/31 09:00
PHST- 2008/04/17 00:00 [received]
PHST- 2008/06/12 00:00 [accepted]
PHST- 2009/07/31 09:00 [entrez]
PHST- 2009/07/31 09:00 [pubmed]
PHST- 2009/10/29 06:00 [medline]
AID - 000224871 [pii]
AID - 10.1159/000224871 [doi]
PST - ppublish
SO  - Urol Int. 2009;83(1):66-9. doi: 10.1159/000224871. Epub 2009 Jul 27.