PMID- 19643494
OWN - NLM
STAT- MEDLINE
DCOM- 20090924
LR  - 20220409
IS  - 1549-4713 (Electronic)
IS  - 0161-6420 (Linking)
VI  - 116
IP  - 9
DP  - 2009 Sep
TI  - Correlation between metamorphopsia and epiretinal membrane optical coherence 
      tomography findings.
PG  - 1788-93
LID - 10.1016/j.ophtha.2009.04.046 [doi]
AB  - PURPOSE: To examine the retinal morphologic features of metamorphopsia caused by 
      epiretinal membrane (ERM) and to determine whether spectral-domain optical 
      coherence tomography (SD-OCT) correlated with metamorphopsia. DESIGN: 
      Retrospective case series. PARTICIPANTS: This study included 19 eyes of 19 
      patients with ERM diagnosed by clinical ophthalmic findings and SD-OCT. METHODS: 
      The 19 eyes were classified into 3 groups based on Amsler chart results: no 
      metamorphopsia (n = 4), local metamorphopsia (n = 8), and broad metamorphopsia (n 
      = 7). The thickness of the 3 inner retinal layers: inner nuclear layer (INL), 
      outer plexiform layer (OPL), and outer nuclear layer (ONL), on 5 horizontal 
      SD-OCT cross-sections (1 line through the fovea, 2 regularly spaced lines 
      superior to the fovea, and 2 regularly spaced lines inferior to the fovea) were 
      measured using the electronic calipers of the SD-OCT system. MAIN OUTCOME 
      MEASURES: Correlation between INL, OPL, and ONL thickness with metamorphopsia and 
      visual acuity. RESULTS: Metamorphopsia was detected in the same position as 
      edematous areas of the INL with a thickness >50 mum. The maximum INL thickness 
      was relatively significantly different between the subjects with no 
      metamorphopsia and those with local or broad metamorphopsia (vs local, P = 0.06; 
      vs broad, P = 0.04). Visual acuity significantly correlated with both maximum INL 
      thickness (A = -0.681; P = 0.001) and maximum ONL thickness (A = -0.708; P<0.001) 
      in metamorphopsia. CONCLUSIONS: Metamorphopsia induced by ERM may be related to 
      the edematous areas of the INL detected with SD-OCT. The classification of ERM 
      based on INL thickness is a potentially useful indication for surgery. FINANCIAL 
      DISCLOSURE(S): The authors have no proprietary or commercial interest in any of 
      the materials discussed in this article.
FAU - Watanabe, Akinari
AU  - Watanabe A
AD  - Nishi Eye Hospital, 4-14-26 Nakamichi, Higashinari, Osaka, Japan. 
      akinari@watanabeeye.net
FAU - Arimoto, Sachiko
AU  - Arimoto S
FAU - Nishi, Okihiro
AU  - Nishi O
LA  - eng
PT  - Journal Article
DEP - 20090730
PL  - United States
TA  - Ophthalmology
JT  - Ophthalmology
JID - 7802443
SB  - IM
CIN - Ophthalmology. 2010 Aug;117(8):1657; author reply 1657. PMID: 20682383
MH  - Aged
MH  - Aged, 80 and over
MH  - Epiretinal Membrane/complications/*diagnosis
MH  - Female
MH  - Humans
MH  - Imaging, Three-Dimensional
MH  - Macular Edema/*diagnosis
MH  - Male
MH  - Middle Aged
MH  - Retinal Neurons/*pathology
MH  - Retrospective Studies
MH  - Tomography, Optical Coherence/*methods
MH  - Vision Disorders/*diagnosis/etiology
MH  - Vision Tests/instrumentation
MH  - Visual Acuity
EDAT- 2009/08/01 09:00
MHDA- 2009/09/25 06:00
CRDT- 2009/08/01 09:00
PHST- 2008/10/05 00:00 [received]
PHST- 2009/04/25 00:00 [revised]
PHST- 2009/04/28 00:00 [accepted]
PHST- 2009/08/01 09:00 [entrez]
PHST- 2009/08/01 09:00 [pubmed]
PHST- 2009/09/25 06:00 [medline]
AID - S0161-6420(09)00475-8 [pii]
AID - 10.1016/j.ophtha.2009.04.046 [doi]
PST - ppublish
SO  - Ophthalmology. 2009 Sep;116(9):1788-93. doi: 10.1016/j.ophtha.2009.04.046. Epub 
      2009 Jul 30.