PMID- 19646504 OWN - NLM STAT- MEDLINE DCOM- 20091215 LR - 20191210 IS - 1873-6246 (Electronic) IS - 0301-0511 (Linking) VI - 82 IP - 3 DP - 2009 Dec TI - Fast multi-feature paradigm for recording several mismatch negativities (MMNs) to phonetic and acoustic changes in speech sounds. PG - 219-26 LID - 10.1016/j.biopsycho.2009.07.008 [doi] AB - In this study, we addressed whether a new fast multi-feature mismatch negativity (MMN) paradigm can be used for determining the central auditory discrimination accuracy for several acoustic and phonetic changes in speech sounds. We recorded the MMNs in the multi-feature paradigm to changes in syllable intensity, frequency, and vowel length, as well as for consonant and vowel change, and compared these MMNs to those obtained with the traditional oddball paradigm. In addition, we examined the reliability of the multi-feature paradigm by repeating the recordings with the same subjects 1-7 days after the first recordings. The MMNs recorded with the multi-feature paradigm were similar to those obtained with the oddball paradigm. Furthermore, only minor differences were observed in the MMN amplitudes across the two recording sessions. Thus, this new multi-feature paradigm with speech stimuli provides similar results as the oddball paradigm, and the MMNs recorded with the new paradigm were reproducible. FAU - Pakarinen, Satu AU - Pakarinen S AD - Cognitive Brain Research Unit, University of Helsinki, Helsinki, Finland; Helsinki Brain Research Centre, Helsinki, Finland. satu.pakarinen@helsinki.fi FAU - Lovio, Riikka AU - Lovio R FAU - Huotilainen, Minna AU - Huotilainen M FAU - Alku, Paavo AU - Alku P FAU - Naatanen, Risto AU - Naatanen R FAU - Kujala, Teija AU - Kujala T LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20090729 PL - Netherlands TA - Biol Psychol JT - Biological psychology JID - 0375566 SB - IM MH - Acoustic Stimulation MH - Adult MH - Analysis of Variance MH - Attention/physiology MH - Auditory Pathways/*physiology MH - Brain/*physiology MH - Discrimination, Psychological/*physiology MH - Electroencephalography MH - Evoked Potentials, Auditory/*physiology MH - Female MH - Humans MH - Language MH - Language Tests MH - Male MH - Neuropsychological Tests MH - Phonetics MH - Psychomotor Performance/physiology MH - Reaction Time/physiology MH - Signal Processing, Computer-Assisted MH - Sound Localization/physiology MH - Speech Perception/*physiology MH - Vocabulary EDAT- 2009/08/04 09:00 MHDA- 2009/12/16 06:00 CRDT- 2009/08/04 09:00 PHST- 2008/06/27 00:00 [received] PHST- 2009/07/15 00:00 [revised] PHST- 2009/07/21 00:00 [accepted] PHST- 2009/08/04 09:00 [entrez] PHST- 2009/08/04 09:00 [pubmed] PHST- 2009/12/16 06:00 [medline] AID - S0301-0511(09)00156-2 [pii] AID - 10.1016/j.biopsycho.2009.07.008 [doi] PST - ppublish SO - Biol Psychol. 2009 Dec;82(3):219-26. doi: 10.1016/j.biopsycho.2009.07.008. Epub 2009 Jul 29.