PMID- 19649639
OWN - NLM
STAT- MEDLINE
DCOM- 20100702
LR  - 20211020
IS  - 1433-8726 (Electronic)
IS  - 0724-4983 (Linking)
VI  - 28
IP  - 2
DP  - 2010 Apr
TI  - Transurethral 2-microm laser in the treatment of urethral stricture.
PG  - 173-5
LID - 10.1007/s00345-009-0454-5 [doi]
AB  - OBJECTIVES: To evaluate the curative efficacy of transurethral 2-mum thulium 
      laser urethrotomy in the treatment of urethral stricture. METHODS: Two hundred 
      and thirty-eight patients suffering from urethral stricture, all male, aged 47.3 
      (36-58), underwent transurethral 2-mum thulium laser urethrotomy. The maximum 
      flow rate (MFR), the international prostatic symptom score (IPSS) and the quality 
      of life (QoL) were measured before operation, immediately following the removal 
      of the catheter, and 3 and 6 months postoperatively. RESULTS: The surgery was 
      performed for all the patients with no rectum injury, urine leakage or massive 
      blood loss. All the patients got free urination immediately following the 
      catheter removal with the mean MFR improved from (3.2 + or - 0.3) ml/s 
      preoperatively to (16.7 + or - 3.1) ml/s, which kept steady to (18.7 + or - 2.9) 
      and (19.2 + or - 2.8) ml/s, respectively 3 and 6 months after operation. IPSS 
      significantly improved from 28.3 + or - 5.8 preoperatively to 7.1 + or - 1.9, 6.4 
      + or - 1.5 and 5.3 + or - 1.3, respectively when catheter removal and 3 and 6 
      months after operation. Also during the corresponding period, mean QoL improved 
      from 5.4 + or - 1.1 to 1.1 + or - 0.3, 0.9 + or - 0.2 and 0.8 + or - 0.2. 195, 
      patients got permanent uninterrupted urination without recurrence in the whole 6 
      months of follow-up. Forty-three patients got recurrence and seven patients 
      encountered with incontinence 1-3 weeks (mean 13.8 days) after catheter removal, 
      but they all got final cure after periodic urethral dilatation and physical 
      exercise. CONCLUSIONS: Transurethral 2-mum thulium laser is safe and efficient in 
      the treatment of urethral stricture.
FAU - Guo, Feng Fu
AU  - Guo FF
AD  - Department of Urology, Linyi People's Hospital, Jiefang Road No. 27 (East), 
      Linyi, Shandong, China.
FAU - Lu, Hua
AU  - Lu H
FAU - Wang, Guang Jian
AU  - Wang GJ
FAU - Tan, Shan Feng
AU  - Tan SF
FAU - He, Xiang Fei
AU  - He XF
FAU - Wang, Jian Ming
AU  - Wang JM
FAU - Liu, Hong Jun
AU  - Liu HJ
FAU - Zhu, Wen Bin
AU  - Zhu WB
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
DEP - 20090802
PL  - Germany
TA  - World J Urol
JT  - World journal of urology
JID - 8307716
RN  - 8RKC5ATI4P (Thulium)
SB  - IM
MH  - Adult
MH  - Dilatation
MH  - Follow-Up Studies
MH  - Humans
MH  - Laser Therapy/*instrumentation/methods
MH  - *Lasers, Solid-State
MH  - Male
MH  - Middle Aged
MH  - Postoperative Complications/therapy
MH  - Quality of Life
MH  - Recurrence
MH  - *Thulium
MH  - Treatment Outcome
MH  - Urethral Stricture/*surgery
MH  - Urinary Incontinence/therapy
EDAT- 2009/08/04 09:00
MHDA- 2010/07/03 06:00
CRDT- 2009/08/04 09:00
PHST- 2009/04/08 00:00 [received]
PHST- 2009/07/07 00:00 [accepted]
PHST- 2009/08/04 09:00 [entrez]
PHST- 2009/08/04 09:00 [pubmed]
PHST- 2010/07/03 06:00 [medline]
AID - 10.1007/s00345-009-0454-5 [doi]
PST - ppublish
SO  - World J Urol. 2010 Apr;28(2):173-5. doi: 10.1007/s00345-009-0454-5. Epub 2009 Aug 
      2.