PMID- 19658448
OWN - NLM
STAT- MEDLINE
DCOM- 20091013
LR  - 20090807
IS  - 1175-0561 (Print)
IS  - 1175-0561 (Linking)
VI  - 10
IP  - 5
DP  - 2009
TI  - Intravenous immunoglobulin-induced, non-eczematous, vesiculobullous eruptions in 
      Stevens-Johnson syndrome.
PG  - 339-42
LID - 10.2165/11310610-000000000-00000 [doi]
AB  - Intravenous immunoglobulin (IVIG) has emerged as a promising treatment that 
      interrupts the progression of Stevens-Johnson syndrome (SJS). Our patient 
      experienced an uncommon adverse effect, non-eczematous, vesiculobullous 
      eruptions, after treatment with IVIG. These new lesions developed rapidly on the 
      palms while most previous SJS bullous lesions subsided. A skin biopsy of these 
      new lesions showed an intracorneal vesicle, without epidermal necrosis, with 
      inflammatory cell infiltration. IVIG-induced, vesiculobullous eruptions are 
      discussed, along with their possible pathogenesis. With the increasing use of 
      IVIG for treatment of bullous dermatoses, recognition of this rare adverse effect 
      is important for prompt differential diagnosis.
FAU - Lin, Wan-Lung
AU  - Lin WL
AD  - Department of Dermatology, Chang Gung Memorial Hospital, Taipei, Taiwan.
FAU - Lin, Wen-Chi
AU  - Lin WC
FAU - Chang, Ya-Ching
AU  - Chang YC
FAU - Yang, Li-Cheng
AU  - Yang LC
FAU - Hung, Shuen-Iu
AU  - Hung SI
FAU - Hong, Hong-Shang
AU  - Hong HS
FAU - Chung, Wen-Hung
AU  - Chung WH
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - New Zealand
TA  - Am J Clin Dermatol
JT  - American journal of clinical dermatology
JID - 100895290
RN  - 0 (Immunoglobulins, Intravenous)
RN  - 0 (Immunologic Factors)
SB  - IM
MH  - Biopsy
MH  - Diagnosis, Differential
MH  - Female
MH  - Hand Dermatoses/chemically induced/diagnosis
MH  - Humans
MH  - Immunoglobulins, Intravenous/*adverse effects/therapeutic use
MH  - Immunologic Factors/adverse effects/therapeutic use
MH  - Middle Aged
MH  - Skin Diseases, Vesiculobullous/*chemically induced/diagnosis
MH  - Stevens-Johnson Syndrome/*drug therapy
EDAT- 2009/08/08 09:00
MHDA- 2009/10/14 06:00
CRDT- 2009/08/08 09:00
PHST- 2009/08/08 09:00 [entrez]
PHST- 2009/08/08 09:00 [pubmed]
PHST- 2009/10/14 06:00 [medline]
AID - 9 [pii]
AID - 10.2165/11310610-000000000-00000 [doi]
PST - ppublish
SO  - Am J Clin Dermatol. 2009;10(5):339-42. doi: 10.2165/11310610-000000000-00000.