PMID- 19659654 OWN - NLM STAT- MEDLINE DCOM- 20100118 LR - 20090807 IS - 1440-1843 (Electronic) IS - 1323-7799 (Linking) VI - 14 IP - 5 DP - 2009 Jul TI - Pulmonary manifestations of light chain deposition disease. PG - 767-70 LID - 10.1111/j.1440-1843.2009.01560.x [doi] AB - Light chain deposition disease (LCDD) is a rare condition characterized by extracellular light chain deposition in tissues. Patients commonly have an underlying plasma cell dyscrasia, and produce excess levels of monoclonal light chains. Renal involvement is the most common clinical manifestation. Rarely, light chains are deposited in the lung. We present the pathologic and radiographic findings of three patients with biopsy-proven pulmonary light chain disease and a review of the literature. FAU - Rho, Lisa AU - Rho L AD - Division of Pulmonary, Critical Care and Sleep Medicine, New York, USA. lisa.rho@mssm.edu FAU - Qiu, Libo AU - Qiu L FAU - Strauchen, James A AU - Strauchen JA FAU - Gordon, Ronald E AU - Gordon RE FAU - Teirstein, Alvin S AU - Teirstein AS LA - eng PT - Case Reports PT - Journal Article PT - Review PL - Australia TA - Respirology JT - Respirology (Carlton, Vic.) JID - 9616368 RN - 0 (Immunoglobulin Light Chains) SB - IM MH - Adult MH - Aged, 80 and over MH - Biopsy MH - Female MH - Humans MH - Immunoglobulin Light Chains/*metabolism MH - Lung/immunology/pathology MH - Lung Diseases/*diagnosis/etiology/*immunology MH - Male MH - Middle Aged MH - Paraproteinemias/complications RF - 15 EDAT- 2009/08/08 09:00 MHDA- 2010/01/19 06:00 CRDT- 2009/08/08 09:00 PHST- 2009/08/08 09:00 [entrez] PHST- 2009/08/08 09:00 [pubmed] PHST- 2010/01/19 06:00 [medline] AID - RES1560 [pii] AID - 10.1111/j.1440-1843.2009.01560.x [doi] PST - ppublish SO - Respirology. 2009 Jul;14(5):767-70. doi: 10.1111/j.1440-1843.2009.01560.x.