PMID- 19672087
OWN - NLM
STAT- MEDLINE
DCOM- 20100204
LR  - 20091015
IS  - 1423-002X (Electronic)
IS  - 0378-7346 (Linking)
VI  - 68
IP  - 3
DP  - 2009
TI  - Impaired glucose metabolism in women with polycystic ovary syndrome.
PG  - 186-90
LID - 10.1159/000232574 [doi]
AB  - BACKGROUND: To compare the prevalence of impaired glucose tolerance (IGT) and 
      type 2 diabetes mellitus (T2DM) in lean and overweight/obese women with 
      polycystic ovary syndrome (PCOS), with the data from a normal population sample. 
      METHODS: PCOS-affected women fulfilling ESHRE diagnostic criteria underwent an 
      oral glucose tolerance test. Prevalence of IGT and T2DM in control sample of 
      white healthy females was extracted from the published data from NHANES II. 
      RESULTS: In 225 women with PCOS, IGT was present in 6/104 (5.8%) lean and in 
      15/121 (12.4%) overweight/obese women. T2DM was present in 1/104 (1.0%) lean and 
      in 3/121 (2.5%) overweight/obese PCOS women. In a sample of 643 women from NHANES 
      II, the crude rate of IGT was 5.9%. IGT was significantly more common only in the 
      overweight/obese PCOS subgroup as compared to the NHANES II cohort (chi(2) = 
      5.99, p < 0.01). CONCLUSIONS: IGT was found significantly more frequently only in 
      overweight/obese PCOS subjects in comparison with healthy controls.
FAU - Vrbikova, Jana
AU  - Vrbikova J
AD  - Institute of Endocrinology, General Faculty Hospital, Charles University, Prague, 
      Czech Republic. jvrbikova@endo.cz
FAU - Fanta, Michal
AU  - Fanta M
FAU - Cibula, David
AU  - Cibula D
FAU - Vondra, Karel
AU  - Vondra K
FAU - Bendlova, Bela
AU  - Bendlova B
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20090807
PL  - Switzerland
TA  - Gynecol Obstet Invest
JT  - Gynecologic and obstetric investigation
JID - 7900587
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Adult
MH  - Blood Glucose/*metabolism
MH  - Diabetes Mellitus, Type 2/blood/epidemiology
MH  - Female
MH  - Glucose Intolerance/*blood
MH  - Glucose Tolerance Test
MH  - Humans
MH  - Obesity/blood
MH  - Polycystic Ovary Syndrome/*blood
MH  - Prevalence
MH  - Retrospective Studies
MH  - Young Adult
EDAT- 2009/08/13 09:00
MHDA- 2010/02/05 06:00
CRDT- 2009/08/13 09:00
PHST- 2008/11/10 00:00 [received]
PHST- 2009/03/02 00:00 [accepted]
PHST- 2009/08/13 09:00 [entrez]
PHST- 2009/08/13 09:00 [pubmed]
PHST- 2010/02/05 06:00 [medline]
AID - 000232574 [pii]
AID - 10.1159/000232574 [doi]
PST - ppublish
SO  - Gynecol Obstet Invest. 2009;68(3):186-90. doi: 10.1159/000232574. Epub 2009 Aug 
      7.