PMID- 196730
OWN - NLM
STAT- MEDLINE
DCOM- 19771028
LR  - 20190720
IS  - 0008-4166 (Print)
IS  - 0008-4166 (Linking)
VI  - 23
IP  - 8
DP  - 1977 Aug
TI  - The effect of the antiherpesvirus drug 5-methoxymethyl-2'-deoxyuridine on the 
      humoral immune response in vivo.
PG  - 1059-61
AB  - 5-Methoxymethyl-2'-deoxyuridine (MMUdR), a drug with potent antiviral activity in 
      vitro against Herpes simplex virus, was investigated for its immunosuppressive 
      effects. Doses as high as 2000mg/kg given daily for 9 days were not 
      immunosupporessive as judged by the fact that treated animals produced normal 
      immune responses to sheep erythrocytes, Brucella bacteria, and Herpes simplex 
      virus.
FAU - Rouse, B T
AU  - Rouse BT
FAU - Babiuk, L A
AU  - Babiuk LA
FAU - Gupta, V S
AU  - Gupta VS
LA  - eng
PT  - Journal Article
PL  - Canada
TA  - Can J Microbiol
JT  - Canadian journal of microbiology
JID - 0372707
RN  - 0 (Antibodies, Bacterial)
RN  - 0 (Antibodies, Viral)
RN  - 0 (Antigens, Bacterial)
RN  - 0 (Antigens, Viral)
RN  - 0 (Antiviral Agents)
RN  - 0 (Immunosuppressive Agents)
RN  - W78I7AY22C (Deoxyuridine)
SB  - IM
MH  - Animals
MH  - Antibodies, Bacterial/biosynthesis
MH  - Antibodies, Viral/biosynthesis
MH  - Antibody Formation/*drug effects
MH  - Antibody-Producing Cells/drug effects
MH  - Antigens, Bacterial
MH  - Antigens, Viral
MH  - Antiviral Agents/*pharmacology
MH  - Brucella abortus/immunology
MH  - Deoxyuridine/*analogs & derivatives/pharmacology
MH  - Erythrocytes/immunology
MH  - *Immunosuppressive Agents
MH  - Mice
MH  - Sheep/immunology
MH  - Simplexvirus/immunology
MH  - Spleen/immunology
EDAT- 1977/08/01 00:00
MHDA- 1977/08/01 00:01
CRDT- 1977/08/01 00:00
PHST- 1977/08/01 00:00 [pubmed]
PHST- 1977/08/01 00:01 [medline]
PHST- 1977/08/01 00:00 [entrez]
AID - 10.1139/m77-158 [doi]
PST - ppublish
SO  - Can J Microbiol. 1977 Aug;23(8):1059-61. doi: 10.1139/m77-158.