PMID- 19681708
OWN - NLM
STAT- MEDLINE
DCOM- 20091105
LR  - 20220330
IS  - 1537-6591 (Electronic)
IS  - 1058-4838 (Linking)
VI  - 49
IP  - 6
DP  - 2009 Sep 15
TI  - Cryptococcal immune reconstitution inflammatory syndrome after antiretroviral 
      therapy in AIDS patients with cryptococcal meningitis: a prospective multicenter 
      study.
PG  - 931-4
LID - 10.1086/605497 [doi]
AB  - A prospective multicenter study of cryptococcal immune reconstitution 
      inflammatory syndrome (IRIS) was conducted as a substudy of the Bacteriology and 
      Mycology Study Group 3-01. Of 101 AIDS patients with cryptococcal meningitis who 
      received highly active antiretroviral therapy (HAART), 13 experienced 
      cryptococcal IRIS. No association between the timing of HAART initiation and the 
      diagnosis of IRIS was identified. Increased baseline serum cryptococcal antigen 
      (CrAg) titer was a risk factor for cryptococcal IRIS.
FAU - Sungkanuparph, Somnuek
AU  - Sungkanuparph S
AD  - Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand. rasuy@mahidol.ac.th
FAU - Filler, Scott G
AU  - Filler SG
FAU - Chetchotisakd, Ploenchan
AU  - Chetchotisakd P
FAU - Pappas, Peter G
AU  - Pappas PG
FAU - Nolen, Tracy L
AU  - Nolen TL
FAU - Manosuthi, Weerawat
AU  - Manosuthi W
FAU - Anekthananon, Thanomsak
AU  - Anekthananon T
FAU - Morris, Michele I
AU  - Morris MI
FAU - Supparatpinyo, Khuanchai
AU  - Supparatpinyo K
FAU - Kopetskie, Heather
AU  - Kopetskie H
FAU - Kendrick, Amy S
AU  - Kendrick AS
FAU - Johnson, Philip C
AU  - Johnson PC
FAU - Sobel, Jack D
AU  - Sobel JD
FAU - Larsen, Robert A
AU  - Larsen RA
LA  - eng
GR  - 5R01AI1070091/AI/NIAID NIH HHS/United States
GR  - N01 AI-15440/AI/NIAID NIH HHS/United States
GR  - N01 AI-15441/AI/NIAID NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, N.I.H., Extramural
PL  - United States
TA  - Clin Infect Dis
JT  - Clinical infectious diseases : an official publication of the Infectious Diseases 
      Society of America
JID - 9203213
RN  - 0 (Anti-HIV Agents)
RN  - 0 (Antifungal Agents)
RN  - 0 (Antigens, Fungal)
RN  - 7XU7A7DROE (Amphotericin B)
RN  - 8VZV102JFY (Fluconazole)
SB  - IM
MH  - AIDS-Related Opportunistic Infections/blood/*complications/drug 
      therapy/microbiology
MH  - Acquired Immunodeficiency Syndrome/blood/*complications/drug therapy/microbiology
MH  - Amphotericin B/therapeutic use
MH  - Anti-HIV Agents/*adverse effects/therapeutic use
MH  - Antifungal Agents/therapeutic use
MH  - Antigens, Fungal/blood
MH  - Antiretroviral Therapy, Highly Active
MH  - Clinical Trials, Phase II as Topic
MH  - Fluconazole/therapeutic use
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/blood/*complications/drug 
      therapy/epidemiology
MH  - Immunocompromised Host
MH  - Incidence
MH  - Kaplan-Meier Estimate
MH  - Logistic Models
MH  - Meningitis, Cryptococcal/blood/*complications/drug therapy/epidemiology
MH  - Proportional Hazards Models
MH  - Prospective Studies
MH  - Randomized Controlled Trials as Topic
MH  - Risk Factors
MH  - Time Factors
EDAT- 2009/08/18 09:00
MHDA- 2009/11/06 06:00
CRDT- 2009/08/18 09:00
PHST- 2009/08/18 09:00 [entrez]
PHST- 2009/08/18 09:00 [pubmed]
PHST- 2009/11/06 06:00 [medline]
AID - 10.1086/605497 [doi]
PST - ppublish
SO  - Clin Infect Dis. 2009 Sep 15;49(6):931-4. doi: 10.1086/605497.