PMID- 19687041
OWN - NLM
STAT- MEDLINE
DCOM- 20091203
LR  - 20221207
IS  - 1471-2970 (Electronic)
IS  - 0962-8436 (Print)
IS  - 0962-8436 (Linking)
VI  - 364
IP  - 1530
DP  - 2009 Sep 27
TI  - Avian influenza virus, Streptococcus suis serotype 2, severe acute respiratory 
      syndrome-coronavirus and beyond: molecular epidemiology, ecology and the 
      situation in China.
PG  - 2725-37
LID - 10.1098/rstb.2009.0093 [doi]
AB  - The outbreak and spread of severe acute respiratory syndrome-associated 
      coronavirus and the subsequent identification of its animal origin study have 
      heightened the world's awareness of animal-borne or zoonotic pathogens. In 
      addition to SARS, the highly pathogenic avian influenza virus (AIV), H5N1, and 
      the lower pathogenicity H9N2 AIV have expanded their host ranges to infect human 
      beings and other mammalian species as well as birds. Even the 'well-known' 
      reservoir animals for influenza virus, migratory birds, became victims of the 
      highly pathogenic H5N1 virus. Not only the viruses, but bacteria can also expand 
      their host range: a new disease, streptococcal toxic shock syndrome, caused by 
      human Streptococcus suis serotype 2 infection, has been observed in China with 52 
      human fatalities in two separate outbreaks (1998 and 2005, respectively). 
      Additionally, enterohaemorrhagic Escherichia coli O157:H7 infection has increased 
      worldwide with severe disease. Several outbreaks and sporadic isolations of this 
      pathogen in China have made it an important target for disease control. A new 
      highly pathogenic variant of porcine reproductive and respiratory syndrome virus 
      (PRRSV) has been isolated in both China and Vietnam recently; although PRRSV is 
      not a zoonotic human pathogen, its severe outbreaks have implications for food 
      safety. All of these pathogens occur in Southeast Asia, including China, with 
      severe consequences; therefore, we discuss the issues in this article by 
      addressing the situation of the zoonotic threat in China.
FAU - Ma, Ying
AU  - Ma Y
AD  - CAS Key Laboratory of Pathogenic Microbiology and Immunology (CASPMI), Institute 
      of Microbiology, Chinese Academy of Sciences (CAS), Beijing 100101, The People's 
      Republic of China.
FAU - Feng, Youjun
AU  - Feng Y
FAU - Liu, Di
AU  - Liu D
FAU - Gao, George F
AU  - Gao GF
LA  - eng
GR  - U19 AI051915/AI/NIAID NIH HHS/United States
GR  - U19 AI051915-05S10/AI/NIAID NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Philos Trans R Soc Lond B Biol Sci
JT  - Philosophical transactions of the Royal Society of London. Series B, Biological 
      sciences
JID - 7503623
SB  - IM
MH  - Animals
MH  - China/epidemiology
MH  - Ecosystem
MH  - Escherichia coli Infections/*epidemiology/microbiology
MH  - Escherichia coli O157/isolation & purification
MH  - Humans
MH  - Influenza A Virus, H5N1 Subtype/isolation & purification
MH  - Influenza, Human/*epidemiology/virology
MH  - Molecular Epidemiology
MH  - Severe acute respiratory syndrome-related coronavirus/isolation & purification
MH  - Severe Acute Respiratory Syndrome/*epidemiology/virology
MH  - Streptococcal Infections/*epidemiology/microbiology
MH  - Streptococcus/isolation & purification
MH  - Zoonoses/*epidemiology/virology
PMC - PMC2865088
EDAT- 2009/08/19 09:00
MHDA- 2009/12/16 06:00
PMCR- 2009/09/27
CRDT- 2009/08/19 09:00
PHST- 2009/08/19 09:00 [entrez]
PHST- 2009/08/19 09:00 [pubmed]
PHST- 2009/12/16 06:00 [medline]
PHST- 2009/09/27 00:00 [pmc-release]
AID - 364/1530/2725 [pii]
AID - rstb20090093 [pii]
AID - 10.1098/rstb.2009.0093 [doi]
PST - ppublish
SO  - Philos Trans R Soc Lond B Biol Sci. 2009 Sep 27;364(1530):2725-37. doi: 
      10.1098/rstb.2009.0093.