PMID- 19691782 OWN - NLM STAT- MEDLINE DCOM- 20091117 LR - 20090820 IS - 1443-1661 (Electronic) IS - 0915-5635 (Linking) VI - 21 IP - 2 DP - 2009 Apr TI - Case of inflammatory fibroid polyp of the esophagogastric junction. PG - 97-100 LID - 10.1111/j.1443-1661.2009.00833.x [doi] AB - Upper gastrointestinal endoscopy of a 25-year-old man with heartburn revealed an elevated lesion in the esophagogastric junction (EGJ). Piecemeal endoscopic mucosal resection (EMR) followed by histopathological examination led to a diagnosis of inflammatory fibroid polyp (IFP). After EMR, the heartburn persisted despite giving a proton pump inhibitor (PPI), and the residual lesion gradually enlarged and a transverse mucosal break developed on the esophageal side of it. However, the combined administration of the PPI and an H2 receptor antagonist reduced the heartburn, and led to endoscopic regression of the lesion and disappearance of the transverse mucosal break. IFP of the esophagogastric junction is extremely rare, and this case is interesting in that potent inhibition of gastric acid secretion resulted in the regression of the lesion. FAU - Yamane, Tateki AU - Yamane T AD - Division of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University Kashiwa Hospital, Kashiwa, Chiba, Japan. yamane@jikei.ac.jp FAU - Uchiyama, Kan AU - Uchiyama K FAU - Ishii, Takayuki AU - Ishii T FAU - Ishii, Hironori AU - Ishii H FAU - Takizawa, Reo AU - Takizawa R FAU - Omura, Mitsuhiro AU - Omura M FAU - Fujise, Kiyotaka AU - Fujise K FAU - Tajiri, Hisao AU - Tajiri H LA - eng PT - Case Reports PT - Journal Article PL - Australia TA - Dig Endosc JT - Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society JID - 9101419 RN - 0 (Histamine H2 Antagonists) RN - 0 (Proton Pump Inhibitors) SB - IM MH - Adult MH - Esophageal Diseases/drug therapy/*pathology/surgery MH - *Esophagogastric Junction MH - Histamine H2 Antagonists/therapeutic use MH - Humans MH - Male MH - Polyps/drug therapy/*pathology/*surgery MH - Proton Pump Inhibitors/radiation effects/therapeutic use MH - Stomach Diseases/drug therapy/*pathology/surgery EDAT- 2009/08/21 09:00 MHDA- 2009/11/18 06:00 CRDT- 2009/08/21 09:00 PHST- 2009/08/21 09:00 [entrez] PHST- 2009/08/21 09:00 [pubmed] PHST- 2009/11/18 06:00 [medline] AID - DEN833 [pii] AID - 10.1111/j.1443-1661.2009.00833.x [doi] PST - ppublish SO - Dig Endosc. 2009 Apr;21(2):97-100. doi: 10.1111/j.1443-1661.2009.00833.x.