PMID- 19702902
OWN - NLM
STAT- MEDLINE
DCOM- 20091102
LR  - 20220408
IS  - 1440-1746 (Electronic)
IS  - 0815-9319 (Linking)
VI  - 24
IP  - 8
DP  - 2009 Aug
TI  - Prevalence of celiac disease in the Asia-Pacific region.
PG  - 1347-51
LID - 10.1111/j.1440-1746.2009.05932.x [doi]
AB  - The development of sensitive and specific serological assays for celiac disease 
      has led to a revision of the prevalence of this disease in many countries. In the 
      Asia-Pacific region, prevalence has been determined in only a minority of 
      countries but those with prevalence rates of 1:50-1:500 adults include Australia, 
      Iran, Israel, New Zealand, Syria and Turkey. In contrast, celiac disease appears 
      to be extremely rare in Japan and may be rare in China. In India, prevalence 
      rates are high in the northern states but much lower in the southern states. In 
      individual countries, important determinants of prevalence include the per capita 
      consumption of wheat and the frequency of a specific human leukocyte antigen 
      (HLA) type genetically defined as HLA-DQB1*02 (*0201 or *0202) and serologically 
      defined as HLA-DQ2. These determinants predict low prevalence rates for celiac 
      disease in the Pacific Islands, South-East Asia and eastern China but higher 
      rates in countries west of India and China. There is also the potential for a 
      rising incidence of celiac disease if traditional rice-based diets are replaced 
      by Western-style diets with a higher content of wheat products.
FAU - Cummins, Adrian G
AU  - Cummins AG
AD  - Department of Gastroenterology and Hepatology, The Queen Elizabeth Hospital, 
      Adelaide, South Australia, Australia. adrian.cummins@health.sa.gov.au
FAU - Roberts-Thomson, Ian C
AU  - Roberts-Thomson IC
LA  - eng
PT  - Journal Article
PL  - Australia
TA  - J Gastroenterol Hepatol
JT  - Journal of gastroenterology and hepatology
JID - 8607909
RN  - 0 (HLA-DQ Antigens)
RN  - 0 (HLA-DQ beta-Chains)
RN  - 0 (HLA-DQ2 antigen)
RN  - 0 (HLA-DQB1 antigen)
RN  - 8002-80-0 (Glutens)
SB  - IM
MH  - Adult
MH  - Asia/epidemiology
MH  - Australia/epidemiology
MH  - Celiac Disease/*ethnology/*etiology
MH  - Child
MH  - Child, Preschool
MH  - Diet/adverse effects
MH  - Genetic Predisposition to Disease
MH  - Glutens/adverse effects
MH  - HLA-DQ Antigens/genetics
MH  - HLA-DQ beta-Chains
MH  - Humans
MH  - Infant
MH  - New Zealand/epidemiology
MH  - Prevalence
MH  - Risk Factors
MH  - Triticum/adverse effects
EDAT- 2009/08/26 09:00
MHDA- 2009/11/03 06:00
CRDT- 2009/08/26 09:00
PHST- 2009/08/26 09:00 [entrez]
PHST- 2009/08/26 09:00 [pubmed]
PHST- 2009/11/03 06:00 [medline]
AID - JGH5932 [pii]
AID - 10.1111/j.1440-1746.2009.05932.x [doi]
PST - ppublish
SO  - J Gastroenterol Hepatol. 2009 Aug;24(8):1347-51. doi: 
      10.1111/j.1440-1746.2009.05932.x.