PMID- 19711027
OWN - NLM
STAT- MEDLINE
DCOM- 20100802
LR  - 20100503
IS  - 1559-0720 (Electronic)
IS  - 0163-4984 (Linking)
VI  - 135
IP  - 1-3
DP  - 2010 Jun
TI  - Effect of training judo in the competition period on the plasmatic levels of 
      leptin and pro-inflammatory cytokines in high-performance male athletes.
PG  - 345-54
LID - 10.1007/s12011-009-8499-2 [doi]
AB  - The purpose this study was to evaluate the effect of training judo in the 
      competition period on the plasmatic levels of bioactive molecules in 
      high-performance male athletes. The subjects were divided into two groups, a 
      trained group with 11 judokas and a nontrained group also with 11 subjects. Blood 
      samples obtained 60 h after training to measure plasma tumor necrosis factor 
      (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein 1 (MCP-1), and 
      leptin levels. The trained group presented a significant reduction in the 
      percentage of fat and fat mass and an increase in the lumbar and lower limbs 
      traction forces and the maximum VO(2) when compared to the nontrained group. 
      There was no significant difference in the serum concentrations of TNF-alpha and 
      IL-6 between the two groups. The trained group presented a lower concentration of 
      leptin, both as absolute values as well as relative to the percentage of fat, and 
      a higher concentration of MCP-1, in relation to the nontrained group. Our results 
      suggest an adaptation in the capacity of synthesizing and secreting leptin in 
      response to chronic stress in judo, what suggests a neuro-hormonal adjustment 
      that guarantees the efficiency of metabolism. The changes of MCP-1 indicated a 
      possible inflammatory state.
FAU - de Oliveira, Donizete Cicero Xavier
AU  - de Oliveira DC
AD  - Post Graduate Program-Human Movement Sciences Institute of Physical Activity and 
      Sport Sciences, Cruzeiro do Sul University Sao Paulo, 868 Galvao Bueno Street, 
      Sao Paulo 01506-000, Brazil.
FAU - Rossano Procida, Izildinha
AU  - Rossano Procida I
FAU - das Neves Borges-Silva, Cristina
AU  - das Neves Borges-Silva C
LA  - eng
PT  - Journal Article
DEP - 20090827
PL  - United States
TA  - Biol Trace Elem Res
JT  - Biological trace element research
JID - 7911509
RN  - 0 (Chemokine CCL2)
RN  - 0 (Interleukin-6)
RN  - 0 (Leptin)
RN  - 0 (Tumor Necrosis Factor-alpha)
SB  - IM
MH  - Chemokine CCL2/*blood
MH  - Exercise/*physiology
MH  - Humans
MH  - Interleukin-6/*blood
MH  - Leptin/*blood
MH  - Male
MH  - Martial Arts/*physiology
MH  - Tumor Necrosis Factor-alpha/*blood
MH  - Young Adult
EDAT- 2009/08/28 09:00
MHDA- 2010/08/03 06:00
CRDT- 2009/08/28 09:00
PHST- 2009/05/11 00:00 [received]
PHST- 2009/08/10 00:00 [accepted]
PHST- 2009/08/28 09:00 [entrez]
PHST- 2009/08/28 09:00 [pubmed]
PHST- 2010/08/03 06:00 [medline]
AID - 10.1007/s12011-009-8499-2 [doi]
PST - ppublish
SO  - Biol Trace Elem Res. 2010 Jun;135(1-3):345-54. doi: 10.1007/s12011-009-8499-2. 
      Epub 2009 Aug 27.