PMID- 19725845 OWN - NLM STAT- MEDLINE DCOM- 20100722 LR - 20191210 IS - 1540-8175 (Electronic) IS - 0742-2822 (Linking) VI - 27 IP - 2 DP - 2010 Feb TI - Tricuspid annular velocity assessed by doppler tissue imaging as a marker of right ventricular involvement in the acute and late phase after a first ST elevation myocardial infarction. PG - 139-45 LID - 10.1111/j.1540-8175.2009.00985.x [doi] AB - BACKGROUND: Right ventricular (RV) involvement in patients with ST elevation myocardial infarction (STEMI) is a clinically important problem. The aim of this study was to evaluate the use of tricuspid annular velocity assessed by Doppler tissue imaging (DTI) as a marker of RV involvement in patients with a first STEMI. METHODS: Seventy-one patients with a first STEMI were examined by echocardiography before discharge and after 6 months. The patients were compared to 31 healthy subjects (HS). The diagnosis of RV infarction was based on the presence of >or= 1 mm ST elevation in the right precordial ECG lead V4R. Tricuspid annular systolic and diastolic velocities using pulsed-wave DTI were recorded at the RV free wall. RESULTS: At day 1, tricuspid annular velocities were significantly reduced in patients with, compared to those without, ST elevation in V4R (11.1 vs. 13.7 cm/sec, 9.4 vs. 13.1 cm/sec and 14.1 vs. 15.9 cm/sec for systolic, early, and late diastolic velocities, respectively; P < 0.01). With a cutoff value for a tricuspid annular systolic velocity of 13 cm/sec, sensitivity and specificity for identifying patients with ST elevation in V4R were 89% and 71%, respectively. After 6 months, both tricuspid annular systolic and diastolic velocities in patients with RV infarction had increased significantly, but only tricuspid annular systolic velocity was still reduced compared to HS (12.3 vs. 14.7 cm/sec; P < 0.01). CONCLUSION: Tricuspid annular velocities assessed by DTI may be used as a marker of RV involvement in the acute and the late phase after a first STEMI. FAU - Witt, Nils AU - Witt N AD - Department of Cardiology, Karolinska Institute at South Hospital Sodersjukhuset, Stockholm, Sweden. nils.witt@sodersjukhuset.se FAU - Alam, Mahbubul AU - Alam M FAU - Svensson, Leif AU - Svensson L FAU - Samad, Bassem A AU - Samad BA LA - eng PT - Evaluation Study PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20090831 PL - United States TA - Echocardiography JT - Echocardiography (Mount Kisco, N.Y.) JID - 8511187 SB - IM MH - Echocardiography, Doppler/*methods MH - Female MH - Humans MH - Image Enhancement/methods MH - Image Interpretation, Computer-Assisted/*methods MH - Male MH - Middle Aged MH - Myocardial Infarction/*complications/*diagnostic imaging MH - Reproducibility of Results MH - Sensitivity and Specificity MH - Tricuspid Valve/*diagnostic imaging MH - Ventricular Dysfunction, Right/*diagnostic imaging/*etiology EDAT- 2009/09/04 06:00 MHDA- 2010/07/23 06:00 CRDT- 2009/09/04 06:00 PHST- 2009/09/04 06:00 [entrez] PHST- 2009/09/04 06:00 [pubmed] PHST- 2010/07/23 06:00 [medline] AID - ECHO985 [pii] AID - 10.1111/j.1540-8175.2009.00985.x [doi] PST - ppublish SO - Echocardiography. 2010 Feb;27(2):139-45. doi: 10.1111/j.1540-8175.2009.00985.x. Epub 2009 Aug 31.