PMID- 19726949
OWN - NLM
STAT- MEDLINE
DCOM- 20091207
LR  - 20181201
IS  - 1536-5166 (Electronic)
IS  - 1070-8022 (Linking)
VI  - 29
IP  - 3
DP  - 2009 Sep
TI  - Evaluation of the retinal nerve fiber layer: descriptive or predictive?
PG  - 245-9
LID - 10.1097/WNO.0b013e3181b1b3d7 [doi]
AB  - For nearly a century, ophthalmologists have recognized that thinning of the 
      retinal nerve fiber layer (rNFL) could be observed ophthalmoscopically in 
      diseases of the optic nerve. Using high-resolution red-free fundus photography, 
      Hoyt found slit-like rNFL defects that corresponded to visual field defects in 
      glaucoma. Frisen extended these observations to multiple sclerosis, predicting 
      the later discovery that axonal loss occurs in the retina without clinical bouts 
      of optic neuritis. In measurement of the rNFL, red-free fundus photography has 
      been superseded by more widely available, robust, and quantitative retinal 
      imaging techniques, including Heidelberg retinal tomography, scanning laser 
      polarimetry, and optical coherence tomography (OCT). Having emerged as the 
      technique of choice in measuring the rNFL, OCT has shown that the degree of 
      preoperative rNFL thinning reliably predicts whether vision will recover after 
      surgery for pituitary adenoma. Such quantitative studies of the rNFL have the 
      potential, therefore, of providing descriptive and predictive information that 
      will be valuable in clinical care.
FAU - Savino, Peter J
AU  - Savino PJ
AD  - Shiley Eye Center, University of California-San Diego, 9415 Camp Point Drive, La 
      Jolla, CA 92093-0946, USA. pjsavino@aol.com
LA  - eng
PT  - Case Reports
PT  - Historical Article
PT  - Journal Article
PT  - Lecture
PL  - United States
TA  - J Neuroophthalmol
JT  - Journal of neuro-ophthalmology : the official journal of the North American 
      Neuro-Ophthalmology Society
JID - 9431308
SB  - IM
MH  - Diagnostic Techniques, Ophthalmological/*history/*trends
MH  - Female
MH  - History, 20th Century
MH  - Humans
MH  - Middle Aged
MH  - Optic Nerve Diseases/*diagnosis/*history
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Retina/*pathology/physiopathology
MH  - Retinal Ganglion Cells/pathology
MH  - Tomography, Optical Coherence/trends
MH  - Wallerian Degeneration/pathology/physiopathology
EDAT- 2009/09/04 06:00
MHDA- 2009/12/16 06:00
CRDT- 2009/09/04 06:00
PHST- 2009/09/04 06:00 [entrez]
PHST- 2009/09/04 06:00 [pubmed]
PHST- 2009/12/16 06:00 [medline]
AID - 00041327-200909000-00014 [pii]
AID - 10.1097/WNO.0b013e3181b1b3d7 [doi]
PST - ppublish
SO  - J Neuroophthalmol. 2009 Sep;29(3):245-9. doi: 10.1097/WNO.0b013e3181b1b3d7.