PMID- 19727357 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20100628 LR - 20211020 IS - 1817-1737 (Print) IS - 1998-3557 (Electronic) IS - 1998-3557 (Linking) VI - 2 IP - 3 DP - 2007 Jul TI - Early changes in pulmonary functions after mitral valve replacement. PG - 111-7 LID - 10.4103/1817-1737.33699 [doi] AB - BACKGROUND: This study evaluates changes in pulmonary functions before and after mitral valve replacement (MVR). MATERIALS AND METHODS: Twenty-five patients with rheumatic mitral lesions who had undergone MVR were divided into three groups, based on New York Heart Association (NYHA) class. They were evaluated for changes in pulmonary functions, preoperatively and postoperatively at 1 week, 1 month and 3 months to find any improvements after MVR. RESULTS: Forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), peak expiratory flow rates were universally found to be decreased preoperatively. Total lung capacity (TLC) and diffusion capacity (DLCO) were significantly reduced preoperatively in NYHA Class III and IV. The pulmonary functions further declined at 1 week after surgery. Except for FVC in NYHA Class IV (32.3% improvement, P < 0.05), the changes were statistically insignificant. CONCLUSIONS: Pulmonary functions deteriorate immediately after surgery and then recover gradually over a period of 3 months. However, they remain below the predicted values. FAU - Saxena, Pankaj AU - Saxena P AD - Department of Cardiovascular and Thoracic Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India. FAU - Luthra, Suvitesh AU - Luthra S FAU - Dhaliwal, Rajinder Singh AU - Dhaliwal RS FAU - Rana, Surinder Singh AU - Rana SS FAU - Behera, Digambar AU - Behera D LA - eng PT - Journal Article PL - India TA - Ann Thorac Med JT - Annals of thoracic medicine JID - 101280721 PMC - PMC2732086 OTO - NOTNLM OT - Mitral valve replacement OT - pulmonary function test COIS- Conflict of Interest: None declared. EDAT- 2007/07/01 00:00 MHDA- 2007/07/01 00:01 PMCR- 2007/07/01 CRDT- 2009/09/04 06:00 PHST- 2007/02/27 00:00 [received] PHST- 2007/04/29 00:00 [accepted] PHST- 2009/09/04 06:00 [entrez] PHST- 2007/07/01 00:00 [pubmed] PHST- 2007/07/01 00:01 [medline] PHST- 2007/07/01 00:00 [pmc-release] AID - ATM-02-111 [pii] AID - 10.4103/1817-1737.33699 [doi] PST - ppublish SO - Ann Thorac Med. 2007 Jul;2(3):111-7. doi: 10.4103/1817-1737.33699.