PMID- 19735383
OWN - NLM
STAT- MEDLINE
DCOM- 20100107
LR  - 20220318
IS  - 1365-3148 (Electronic)
IS  - 0958-7578 (Linking)
VI  - 19
IP  - 6
DP  - 2009 Dec
TI  - The EASTR Study: indications for transfusion and estimates of transfusion 
      recipient numbers in hospitals supplied by the National Blood Service.
PG  - 315-28
LID - 10.1111/j.1365-3148.2009.00933.x [doi]
AB  - This study provides data on National Blood Service (NBS) red blood cell (RBC, n = 
      9142), platelet (PLT, n = 4232) and fresh frozen plasma (FFP, n = 3584) 
      recipients independently sampled by monthly quota from 29 representative 
      hospitals over 12 months in 2001-2002. Hospitals were stratified by size 
      according to total yearly RBC issues. Transfusion indications were chosen from 
      diagnostic and procedural codes, and recipients grouped into Epidemiology and 
      Survival of Transfusion Recipients Case-mix Groups (E-CMGs). The main E-CMGs were 
      digestive [19% of RBC recipients; including 5% gastrointestinal (GI) bleeds and 
      3% colorectal surgery], musculoskeletal (15%; 12% hip and knee replacement), 
      haematology (13%) and obstetrics and gynaecology (10%). Renal failure, fractured 
      neck of femur, cardiac artery by-pass grafting (CABG) and paediatrics, each 
      accounted for 3-4% recipients. FFP recipients: the main E-CMGs were digestive 
      (21% of FFP recipients; including 7% GI bleeds and 3% colorectal surgery), 
      hepatobiliary (15%; 7% liver disease and 2% liver transplant), cardiac (12%) and 
      paediatrics (9%) The renal, paediatrics, vascular and haematology E-CMGs each had 
      6-7% of recipients. PLT recipients: the main E-CMGs were haematology (27% of PLT 
      recipients; including 9% lymphoma and 8% acute leukaemia), cardiac (17%), 
      paediatrics (13%), hepatobiliary (10%) and digestive (9%). Back-weighting gave 
      national estimates of 433 000 RBC, 57 500 FFP and 41 500 PLT recipients/year in 
      England and North Wales, median age 69, 64 and 59 years, respectively. Digestive 
      and hepatobiliary indications emerged as the top reason for transfusion in RBC 
      and FFP recipients, and was also a frequent indication in PLT recipients.
FAU - Wells, A W
AU  - Wells AW
AD  - NHS Blood and Transplant (NHSBT), Newcastle upon Tyne, UK. 
      angus.wells@nhsbt.nhs.uk
FAU - Llewelyn, C A
AU  - Llewelyn CA
FAU - Casbard, A
AU  - Casbard A
FAU - Johnson, A J
AU  - Johnson AJ
FAU - Amin, M
AU  - Amin M
FAU - Ballard, S
AU  - Ballard S
FAU - Buck, J
AU  - Buck J
FAU - Malfroy, M
AU  - Malfroy M
FAU - Murphy, M F
AU  - Murphy MF
FAU - Williamson, L M
AU  - Williamson LM
LA  - eng
GR  - MC_U122870183/MRC_/Medical Research Council/United Kingdom
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20090903
PL  - England
TA  - Transfus Med
JT  - Transfusion medicine (Oxford, England)
JID - 9301182
SB  - IM
MH  - Blood Banks
MH  - Blood Transfusion/*statistics & numerical data
MH  - England
MH  - Erythrocyte Transfusion
MH  - Hemorrhage/pathology/*therapy
MH  - Hospitals/*statistics & numerical data
MH  - Humans
MH  - Plasma
MH  - Platelet Transfusion
MH  - Retrospective Studies
MH  - Wales
EDAT- 2009/09/09 06:00
MHDA- 2010/01/08 06:00
CRDT- 2009/09/09 06:00
PHST- 2009/09/09 06:00 [entrez]
PHST- 2009/09/09 06:00 [pubmed]
PHST- 2010/01/08 06:00 [medline]
AID - TME933 [pii]
AID - 10.1111/j.1365-3148.2009.00933.x [doi]
PST - ppublish
SO  - Transfus Med. 2009 Dec;19(6):315-28. doi: 10.1111/j.1365-3148.2009.00933.x. Epub 
      2009 Sep 3.