PMID- 1974589
OWN - NLM
STAT- MEDLINE
DCOM- 19900917
LR  - 20161123
IS  - 0929-6646 (Print)
IS  - 0929-6646 (Linking)
VI  - 89
IP  - 3
DP  - 1990 Mar
TI  - Hemodynamic and clinical efficacies of catheter balloon percutaneous transvenous 
      mitral commissurotomy: experience of 100 patients with rheumatic mitral stenosis.
PG  - 182-9
AB  - From January 1987 to December 1988, 100 patients with symptomatic severe 
      rheumatic mitral stenosis underwent percutaneous transvenous mitral 
      commissurotomy (PTMC). The patients included 32 males and 68 females, aged 19-71 
      years (mean of 41). Mild mitral regurgitation (grade 1 or 2) was present in 23 
      patients and a history of thromboembolism in 12. One patient had had mitral 
      restenosis after surgical open mitral commissurotomy 9 years earlier. The mitral 
      valve was successfully dilated in 97 patients. PTMC resulted in immediate 
      improvements in hemodynamic measurements. The left atrial pressure decreased from 
      24.5 +/- 5.3 to 14.8 +/- 5.2 mmHg (p less than 0.001), the mean mitral 
      transvalvular gradient from 13.8 +/- 4.8 to 5.0 +/- 2.8 mmHg (p less than 0.001), 
      and the mean pulmonary artery pressure from 38.8 +/- 12.0 to 30.6 +/- 10.3 mmHg 
      (p less than 0.001). The mitral valve area increased from 1.1 +/- 0.3 to 2.2 +/- 
      0.8 cm2 (p less than 0.001). The cardiac output increased from 4.5 +/- 1.2 to 
      4.84 +/- 1.2 L/min (p less than 0.05). The right atrial pressure did not change 
      significantly after PTMC (6.5 +/- 3.8 vs 6.4 +/- 4.0 mmHg). The mitral valve area 
      measured by 2-D echocardiograms increased from 1.04 +/- 0.48 to 1.88 +/- 0.66 cm2 
      after PTMC (p less than 0.001). All 97 patients were followed for 6-24 months 
      (median of 13) after the PTMC. After an initial recovery period of 1-2 weeks, all 
      patients reported improvements in symptoms and in New York Heart Association 
      (NYHA) functional class by at least one class. A comparison between treadmill 
      exercise test durations before, and 3 months after PTMC, showed an increase from 
      9.1 +/- 4.3 to 15.4 +/- 3.8 minutes (n = 60; p less than 0.001).(ABSTRACT 
      TRUNCATED AT 250 WORDS)
FAU - Hung, J S
AU  - Hung JS
AD  - Department of Medicine, Chang Gung Memorial Hospital, Taiwan, R.O.C.
FAU - Fu, M
AU  - Fu M
FAU - Yeh, S J
AU  - Yeh SJ
FAU - Lin, F C
AU  - Lin FC
FAU - Cherng, W J
AU  - Cherng WJ
FAU - Yeh, K H
AU  - Yeh KH
FAU - Wu, Y C
AU  - Wu YC
FAU - Wu, D
AU  - Wu D
LA  - eng
PT  - Journal Article
PL  - Singapore
TA  - J Formos Med Assoc
JT  - Journal of the Formosan Medical Association = Taiwan yi zhi
JID - 9214933
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Catheterization/adverse effects
MH  - Echocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - *Hemodynamics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve Insufficiency/diagnostic imaging
MH  - Mitral Valve Stenosis/physiopathology/*therapy
MH  - Radiography
MH  - Rheumatic Heart Disease/physiopathology/*therapy
EDAT- 1990/03/01 00:00
MHDA- 1990/03/01 00:01
CRDT- 1990/03/01 00:00
PHST- 1990/03/01 00:00 [pubmed]
PHST- 1990/03/01 00:01 [medline]
PHST- 1990/03/01 00:00 [entrez]
PST - ppublish
SO  - J Formos Med Assoc. 1990 Mar;89(3):182-9.