PMID- 19755467
OWN - NLM
STAT- MEDLINE
DCOM- 20100312
LR  - 20091120
IS  - 1477-111X (Electronic)
IS  - 0267-6591 (Linking)
VI  - 24
IP  - 3
DP  - 2009 May
TI  - Case control study of gastrointestinal complications after cardiopulmonary bypass 
      heart surgery.
PG  - 173-8
LID - 10.1177/0267659109346665 [doi]
AB  - BACKGROUND: Gastrointestinal complications (GIC) after cardiopulmonary bypass 
      (CPB) surgery are rare, but, nevertheless, extremely dangerous.The identification 
      of risks for GIC may be helpful in planning appropriate perioperative management 
      strategies. The aim of the present study was to analyze perioperative factors of 
      GIC in patients undergoing CPB surgery. METHODS: We retrospectively analysed 206 
      patients who underwent GIC after cardiopulmonary bypass surgery from 2000 to 2007 
      and compared them with 206 matched control patients (matched for surgery, 
      temperature, hemodilution and date). Univariate analysis and multiple logistic 
      regression analysis were performed on 12 risk factors. RESULT: Sex and types of 
      cardioplegia perfusate did not significantly influence the GIC after CPB surgery. 
      Multiple logistic regression revealed that CPB time, preoperative serum 
      creatinine (PSC) > or = 179 mg/dL, emergency surgery, perfusion pressure < or =40 
      mmHg, low cardiac output syndrome (LCOS), age > or = 61, mechanical ventilation > 
      or =96 h, New York Heart Association (NYHA) class III and IV were predictors of 
      the occurrence of GIC after CPB surgery. Perfusion pressure and aprotinin 
      administration were protective factors. CONCLUSION: Gastrointestinal 
      complications after CPB surgery could be predictive in the presence of the above 
      risk factors. This study suggests that GIC can be reduced by maintenance of 
      higher perfusion pressure and shortening the time on CPB and ventilation.
FAU - Zhang, Guowei
AU  - Zhang G
AD  - Department of Cardio-Vascular Surgery, The First Affiliated Hospital of Harbin 
      Medical University, Harbin, China. godway@tom.com
FAU - Wu, Naishi
AU  - Wu N
FAU - Liu, Hongyu
AU  - Liu H
FAU - Lv, Hang
AU  - Lv H
FAU - Yao, Zhifa
AU  - Yao Z
FAU - Li, Junquan
AU  - Li J
LA  - eng
PT  - Journal Article
DEP - 20090915
PL  - England
TA  - Perfusion
JT  - Perfusion
JID - 8700166
SB  - IM
MH  - Adult
MH  - Cardiopulmonary Bypass/*adverse effects
MH  - Case-Control Studies
MH  - Female
MH  - Gastrointestinal Diseases/*etiology/pathology
MH  - Gastrointestinal Tract/*pathology
MH  - Hemodilution
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Perioperative Care
MH  - Prognosis
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Treatment Outcome
MH  - Young Adult
EDAT- 2009/09/17 06:00
MHDA- 2010/03/13 06:00
CRDT- 2009/09/17 06:00
PHST- 2009/09/17 06:00 [entrez]
PHST- 2009/09/17 06:00 [pubmed]
PHST- 2010/03/13 06:00 [medline]
AID - 0267659109346665 [pii]
AID - 10.1177/0267659109346665 [doi]
PST - ppublish
SO  - Perfusion. 2009 May;24(3):173-8. doi: 10.1177/0267659109346665. Epub 2009 Sep 15.