PMID- 19763053 OWN - NLM STAT- MEDLINE DCOM- 20091112 LR - 20120618 IS - 2186-1005 (Electronic) IS - 1341-1098 (Linking) VI - 15 IP - 4 DP - 2009 Aug TI - Reconstructive surgery for an akinetic anterior ventricular wall in ischemic cardiomyopathy. PG - 227-32 AB - BACKGROUND: The purpose of this prospective study is to analyze the postoperative outcome after only left ventricular reconstruction (LVR) versus LVR combined with coronary artery bypass grafting (CABG) and/or mitral valve (MV) procedure in ischemic cardiomyopathy (ICM) as a result of an akinetic anterior ventricular wall. METHODS AND RESULTS: Nineteen patients underwent only LVR, and 37 underwent a concomitant LVR procedure. In both groups, New York Heart Association (NYHA) classification improved significantly from 3.5 +/- 0.6 to 2.2 +/- 0.5 (LVR group) and 3.4 +/- 0.7 to 2.5 +/- 0.5 (combined LVR group). Ejection fraction improved significantly from 25.1 +/- 3.2 to 35.3 +/- 4.5% in the LVR group and 28.1 +/- 2.2 to 37.6 +/- 5.5% in the combined LVR group. Cardiac index improved significantly from 1.8 +/- 0.6 to 2.3 +/- 0.5 l/min/m2 in the LVR group and 1.6 +/- 0.4 to 2.2 +/- 0.6 l/min/m2 in the combined LVR group. An additional concomitant procedure increased the mortality rate only slightly. The overall 1- and 5-year actuarial survival rates were 90% and 75% in the LVR group and 80% and 70% in the combined LVR group. CONCLUSIONS: The LVR for akinetic ventricular wall shows very satisfactory early and long-term results. The LVR, with or without concomitant procedures, has considerable benefits for operative therapy. FAU - Yoda, Masataka AU - Yoda M AD - Department of Thoracic and Cardiovascular Surgery, Heart Center North-Rhine-Westphalia, Ruhr-University of Bochum, Germany. FAU - Tenderich, Gero AU - Tenderich G FAU - Zittermann, Armin AU - Zittermann A FAU - Schulte-Eistrup, Sebastian AU - Schulte-Eistrup S FAU - Al-Deili, Michaele AU - Al-Deili M FAU - Korfer, Reiner AU - Korfer R FAU - Minami, Kazutomo AU - Minami K LA - eng PT - Comparative Study PT - Journal Article PL - Japan TA - Ann Thorac Cardiovasc Surg JT - Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia JID - 9703158 SB - IM MH - *Cardiac Surgical Procedures/adverse effects/mortality MH - Cardiomyopathies/etiology/mortality/physiopathology/*surgery MH - Coronary Artery Bypass MH - Heart Ventricles/physiopathology/surgery MH - Humans MH - Mitral Valve/physiopathology/surgery MH - *Myocardial Contraction MH - Myocardial Ischemia/complications/mortality/physiopathology/*surgery MH - Prospective Studies MH - Recovery of Function MH - Stroke Volume MH - Time Factors MH - Treatment Outcome MH - Ventricular Dysfunction, Left/etiology/mortality/physiopathology/*surgery EDAT- 2009/09/19 06:00 MHDA- 2009/11/13 06:00 CRDT- 2009/09/19 06:00 PHST- 2008/04/03 00:00 [received] PHST- 2008/06/30 00:00 [accepted] PHST- 2009/09/19 06:00 [entrez] PHST- 2009/09/19 06:00 [pubmed] PHST- 2009/11/13 06:00 [medline] AID - atcs/2009_15_1/227 [pii] PST - ppublish SO - Ann Thorac Cardiovasc Surg. 2009 Aug;15(4):227-32.