PMID- 19767793 OWN - NLM STAT- MEDLINE DCOM- 20091015 LR - 20160513 IS - 1715-5312 (Print) IS - 1715-5312 (Linking) VI - 34 IP - 4 DP - 2009 Aug TI - Daily physical activity and macronutrient distribution of low-calorie diets jointly affect body fat reduction in obese women. PG - 595-602 LID - 10.1139/H09-015 [doi] AB - Inadequate dietary patterns and sedentary lifestyles are believed to be important factors in predisposing people to obesity. This study analyzed the potential interaction between habitual physical activity and the carbohydrate (CHO)-fat distribution in 2 hypocaloric diets and the impact of such interplay on body composition changes. Forty healthy obese women, 20-50 years old, were randomly assigned to a high- or low-CHO energy-restricted diet, which was low or high in fat, respectively, during 10 weeks. Baseline and final measurements were performed to assess dietary habits, resting metabolic rate, and body composition changes. Physical activity was measured with a triaxial accelerometer and with a questionnaire. There were no significant differences in anthropometric and metabolic variables between both dietary groups at baseline. However, there was a positive correlation between total free-living physical activity and arm muscle preservation after 10 weeks (r = 0.371; p = 0.024). Interestingly, an interaction between macronutrient (CHO-fat distribution) intake and physical activity was found, since less-active subjects with a high-CHO-low-fat diet showed a greater fat loss than those more active with a lower-CHO-high-fat diet, whereas more-active subjects with a high-CHO-low-fat diet showed a smaller fat loss than those receiving a low-CHO-high-fat diet. Physical activity and the macronutrient content of energy-restricted diets, when designed to promote body fat mass reduction, should be considered together to better predict the outcome. FAU - Lopez-Fontana, Constanza Matilde AU - Lopez-Fontana CM AD - Department of Physiology and Nutrition, University of Navarra, Irunlarrea, Pamplona, Spain. FAU - Sanchez-Villegas, Almudena AU - Sanchez-Villegas A FAU - Martinez-Gonzalez, Miguel Angel AU - Martinez-Gonzalez MA FAU - Martinez, Jose Alfredo AU - Martinez JA LA - eng PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't PL - Canada TA - Appl Physiol Nutr Metab JT - Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme JID - 101264333 RN - 0 (Dietary Carbohydrates) SB - IM MH - *Adiposity MH - Adult MH - Basal Metabolism MH - Body Size MH - *Caloric Restriction MH - Combined Modality Therapy MH - Diet Records MH - *Diet, Fat-Restricted MH - Dietary Carbohydrates/*administration & dosage MH - *Exercise Therapy MH - Female MH - Habits MH - Humans MH - Middle Aged MH - Monitoring, Physiologic/instrumentation MH - Obesity/diet therapy/physiopathology/*therapy MH - Prospective Studies MH - Risk Reduction Behavior MH - Surveys and Questionnaires MH - Time Factors MH - Treatment Outcome MH - Young Adult EDAT- 2009/09/22 06:00 MHDA- 2009/10/16 06:00 CRDT- 2009/09/22 06:00 PHST- 2009/09/22 06:00 [entrez] PHST- 2009/09/22 06:00 [pubmed] PHST- 2009/10/16 06:00 [medline] AID - h09-015 [pii] AID - 10.1139/H09-015 [doi] PST - ppublish SO - Appl Physiol Nutr Metab. 2009 Aug;34(4):595-602. doi: 10.1139/H09-015.