PMID- 19769375 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20100118 LR - 20091014 IS - 1520-6882 (Electronic) IS - 0003-2700 (Linking) VI - 81 IP - 20 DP - 2009 Oct 15 TI - Preparation of micro gold devices on poly(dimethylsiloxane) chips with region-selective electroless plating. PG - 8649-53 LID - 10.1021/ac901539n [doi] AB - A novel protocol for fabrication of micro gold devices on poly(dimethylsiloxane) (PDMS) substrates was developed on the basis of region-selective electroless plating. The layout of a micro gold device was first photochemically patterned onto the PDMS surface through a UV induced poly(acrylic acid) (PAA) grafting process. The carboxylic moieties on the grafted PAA served as the scaffold for a series of wet chemical reactions that led to the immobilization of gold nanoparticles in the UV-exposed region, where electroless plating then occurred under the catalysis of the nanoparticles. Gold devices fabricated with such a protocol could tolerate the Scotch tape test and survive in a repeated bending-straightening test. They also showed good stability in acidic and alkaline solutions, possessed almost the same electrochemical properties as a standard gold disk electrode, and allowed thiol-compounds to form a perfect self-assembled monolayer on their surfaces. The fabricated micro gold electrode was demonstrated to be suitable as the integrated amperometric detection element in a full PDMS micro electrophoresis chip. FAU - Hao, Zhenxia AU - Hao Z AD - Institute of Microanalytical Systems, Department of Chemistry, Zijin'gang Campus, Zhejiang University, Hangzhou 310058, China. FAU - Chen, Hengwu AU - Chen H FAU - Ma, Dan AU - Ma D LA - eng PT - Journal Article PL - United States TA - Anal Chem JT - Analytical chemistry JID - 0370536 EDAT- 2009/09/23 06:00 MHDA- 2009/09/23 06:01 CRDT- 2009/09/23 06:00 PHST- 2009/09/23 06:00 [entrez] PHST- 2009/09/23 06:00 [pubmed] PHST- 2009/09/23 06:01 [medline] AID - 10.1021/ac901539n [doi] PST - ppublish SO - Anal Chem. 2009 Oct 15;81(20):8649-53. doi: 10.1021/ac901539n.