PMID- 19769733
OWN - NLM
STAT- MEDLINE
DCOM- 20091023
LR  - 20211020
IS  - 1749-6632 (Electronic)
IS  - 0077-8923 (Print)
IS  - 0077-8923 (Linking)
VI  - 1174
DP  - 2009 Sep
TI  - Harnessing human dendritic cell subsets to design novel vaccines.
PG  - 24-32
LID - 10.1111/j.1749-6632.2009.04999.x [doi]
AB  - Dendritic cells (DCs) orchestrate a repertoire of immune responses that endow 
      resistance to infection and tolerance to self. DC plasticity and subsets are 
      prominent determinants of the quality of elicited immune responses. Different DC 
      subsets display different receptors and surface molecules and express different 
      sets of cytokines/chemokines, all of which lead to distinct immunological 
      outcomes. Recent findings on human DC subsets and their functional specialization 
      have provided insights for the design of novel human vaccines.
FAU - Banchereau, Jacques
AU  - Banchereau J
AD  - Baylor Institute for Immunology Research, Dallas, TX 75204, USA. 
      jacquesb@baylorhealth.edu
FAU - Klechevsky, Eynav
AU  - Klechevsky E
FAU - Schmitt, Nathalie
AU  - Schmitt N
FAU - Morita, Rimpei
AU  - Morita R
FAU - Palucka, Karolina
AU  - Palucka K
FAU - Ueno, Hideki
AU  - Ueno H
LA  - eng
GR  - U19 AI057234-06S15042/AI/NIAID NIH HHS/United States
GR  - P01 CA084512-05A29004/CA/NCI NIH HHS/United States
GR  - P01 CA084512-07S1/CA/NCI NIH HHS/United States
GR  - P01 CA084512-020003/CA/NCI NIH HHS/United States
GR  - R01 CA085540-02/CA/NCI NIH HHS/United States
GR  - P01 CA084512/CA/NCI NIH HHS/United States
GR  - R01 CA078846-01A1/CA/NCI NIH HHS/United States
GR  - U19 AI057234-05S1/AI/NIAID NIH HHS/United States
GR  - U19 AI057234-03/AI/NIAID NIH HHS/United States
GR  - U19 AI057234-06S3/AI/NIAID NIH HHS/United States
GR  - U19 AI057234-010005/AI/NIAID NIH HHS/United States
GR  - P01 CA084512-069004/CA/NCI NIH HHS/United States
GR  - U19 AI057234-04/AI/NIAID NIH HHS/United States
GR  - R01 CA085540-04/CA/NCI NIH HHS/United States
GR  - U19 AI057234-02/AI/NIAID NIH HHS/United States
GR  - U19 AI057234-05S10012/AI/NIAID NIH HHS/United States
GR  - P01 CA084512-060005/CA/NCI NIH HHS/United States
GR  - R01 CA078846-04/CA/NCI NIH HHS/United States
GR  - U19 AI057234-01/AI/NIAID NIH HHS/United States
GR  - P01 CA084512-01A10003/CA/NCI NIH HHS/United States
GR  - U19 AI057234-06S1/AI/NIAID NIH HHS/United States
GR  - P01 CA084512-030003/CA/NCI NIH HHS/United States
GR  - P01 CA084512-05A2/CA/NCI NIH HHS/United States
GR  - R01 CA078846-05/CA/NCI NIH HHS/United States
GR  - R01 CA085540/CA/NCI NIH HHS/United States
GR  - R01 CA078846-07/CA/NCI NIH HHS/United States
GR  - R01 CA078846-08/CA/NCI NIH HHS/United States
GR  - P01 CA084512-079004/CA/NCI NIH HHS/United States
GR  - U19-AI057234/AI/NIAID NIH HHS/United States
GR  - U19 AI057234-05/AI/NIAID NIH HHS/United States
GR  - R01-CA078846/CA/NCI NIH HHS/United States
GR  - R01 CA078846-10/CA/NCI NIH HHS/United States
GR  - P01 CA084512-06/CA/NCI NIH HHS/United States
GR  - R01 CA078846-06/CA/NCI NIH HHS/United States
GR  - U19 AI057234-010006/AI/NIAID NIH HHS/United States
GR  - R01 CA085540-01A1/CA/NCI NIH HHS/United States
GR  - P01 CA084512-079002/CA/NCI NIH HHS/United States
GR  - P01 CA084512-069002/CA/NCI NIH HHS/United States
GR  - U19 AI057234-05S19003/AI/NIAID NIH HHS/United States
GR  - U19 AI057234-06/AI/NIAID NIH HHS/United States
GR  - R01 CA078846-09/CA/NCI NIH HHS/United States
GR  - R01-CA84512/CA/NCI NIH HHS/United States
GR  - R01 CA078846-02/CA/NCI NIH HHS/United States
GR  - U19 AI057234/AI/NIAID NIH HHS/United States
GR  - U19 AI057234-06S2/AI/NIAID NIH HHS/United States
GR  - P01 CA084512-05A29002/CA/NCI NIH HHS/United States
GR  - R01 CA085540-03/CA/NCI NIH HHS/United States
GR  - U19 AI057234-010004/AI/NIAID NIH HHS/United States
GR  - R01 CA078846-03/CA/NCI NIH HHS/United States
GR  - R01 CA078846/CA/NCI NIH HHS/United States
GR  - U19 AI057234-05S10013/AI/NIAID NIH HHS/United States
GR  - P01 CA084512-070005/CA/NCI NIH HHS/United States
GR  - P01 CA084512-07/CA/NCI NIH HHS/United States
GR  - P01 CA084512-040003/CA/NCI NIH HHS/United States
GR  - P01 CA084512-05A20005/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - United States
TA  - Ann N Y Acad Sci
JT  - Annals of the New York Academy of Sciences
JID - 7506858
RN  - 0 (Antigens, CD)
RN  - 0 (Cancer Vaccines)
RN  - 0 (Cytokines)
RN  - 187348-17-0 (Interleukin-12)
SB  - IM
MH  - Antigens, CD/immunology
MH  - B-Lymphocytes/immunology
MH  - Cancer Vaccines/*immunology
MH  - Cytokines/immunology
MH  - Dendritic Cells/*immunology
MH  - Dermis/immunology
MH  - Drug Design
MH  - Epidermis/immunology
MH  - Humans
MH  - Immunity
MH  - Infections/immunology
MH  - Interleukin-12/immunology
MH  - Langerhans Cells/immunology
MH  - Neoplasms/*immunology
MH  - Self Tolerance
MH  - Skin/immunology
MH  - T-Lymphocytes/immunology
MH  - T-Lymphocytes, Helper-Inducer/immunology
PMC - PMC2759267
MID - NIHMS147794
EDAT- 2009/09/23 06:00
MHDA- 2009/10/24 06:00
PMCR- 2010/09/01
CRDT- 2009/09/23 06:00
PHST- 2009/09/23 06:00 [entrez]
PHST- 2009/09/23 06:00 [pubmed]
PHST- 2009/10/24 06:00 [medline]
PHST- 2010/09/01 00:00 [pmc-release]
AID - NYAS4999 [pii]
AID - 10.1111/j.1749-6632.2009.04999.x [doi]
PST - ppublish
SO  - Ann N Y Acad Sci. 2009 Sep;1174:24-32. doi: 10.1111/j.1749-6632.2009.04999.x.