PMID- 19787547 OWN - NLM STAT- MEDLINE DCOM- 20100811 LR - 20131121 IS - 1747-0927 (Electronic) IS - 1747-0919 (Linking) VI - 5 IP - 2 DP - 2010 TI - Modulation of medial prefrontal and inferior parietal cortices when thinking about past, present, and future selves. PG - 187-200 LID - 10.1080/17470910903233562 [doi] AB - Recent functional neuroimaging studies have shown that reflecting on representations of the present self versus temporally distant selves is associated with higher activity in the medial prefrontal cortex (MPFC). In the current fMRI study, we investigated whether this effect of temporal perspective is symmetrical between the past and future. The main results revealed that the MPFC showed higher activity when reflecting on the present self than when reflecting on past and future selves, with no difference between past and future selves. Temporal perspective also modulated activity in the right inferior parietal cortex but in the opposite direction, activity in this brain region being higher when reflecting on past and future selves relative to the present self (with again no difference between past and future selves). These findings show that differences in brain activity when thinking about current versus temporally distant selves are symmetrical between the past and the future. It is suggested that by processing degrees of self-relatedness, the MPFC might sustain the process of identifying oneself with current representations of the self, whereas the right inferior parietal cortex might be involved in distinguishing the present self from temporally distant selves. FAU - D'Argembeau, Arnaud AU - D'Argembeau A AD - Center for Cognitive and Behavioral Neuroscience, University of Liege, Liege, Belgium. a.dargembeau@ulg.ac.be FAU - Stawarczyk, David AU - Stawarczyk D FAU - Majerus, Steve AU - Majerus S FAU - Collette, Fabienne AU - Collette F FAU - Van der Linden, Martial AU - Van der Linden M FAU - Salmon, Eric AU - Salmon E LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20090921 PL - England TA - Soc Neurosci JT - Social neuroscience JID - 101279009 RN - S88TT14065 (Oxygen) SB - IM MH - Adolescent MH - Adult MH - Analysis of Variance MH - Brain Mapping MH - Female MH - Humans MH - Image Processing, Computer-Assisted/methods MH - Imagination/*physiology MH - Judgment/physiology MH - Magnetic Resonance Imaging/methods MH - Male MH - Mental Recall/*physiology MH - Neuropsychological Tests MH - Oxygen/blood MH - Parietal Lobe/blood supply/*physiology MH - Prefrontal Cortex/blood supply/*physiology MH - Reaction Time/physiology MH - *Self Concept MH - Thinking/*physiology MH - Young Adult EDAT- 2009/09/30 06:00 MHDA- 2010/08/12 06:00 CRDT- 2009/09/30 06:00 PHST- 2009/09/30 06:00 [entrez] PHST- 2009/09/30 06:00 [pubmed] PHST- 2010/08/12 06:00 [medline] AID - 915135845 [pii] AID - 10.1080/17470910903233562 [doi] PST - ppublish SO - Soc Neurosci. 2010;5(2):187-200. doi: 10.1080/17470910903233562. Epub 2009 Sep 21.