PMID- 19787723
OWN - NLM
STAT- MEDLINE
DCOM- 20091217
LR  - 20151119
IS  - 1053-1807 (Print)
IS  - 1053-1807 (Linking)
VI  - 30
IP  - 4
DP  - 2009 Oct
TI  - Multicontrast late gadolinium enhancement imaging enables viability and wall 
      motion assessment in a single acquisition with reduced scan times.
PG  - 771-7
LID - 10.1002/jmri.21907 [doi]
AB  - PURPOSE: To determine the accuracy of multicontrast late enhancement imaging 
      (MCLE) in the assessment of myocardial viability and wall motion compared to the 
      conventional wall motion and viability cardiac magnetic resonance imaging (MRI) 
      pulse sequences. MATERIALS AND METHODS: Forty-one patients with suspected 
      myocardial infarction were studied. Patients underwent assessment of cardiac 
      function with cine steady-state free-precession (SSFP), followed by late 
      gadolinium enhancement (LGE) imaging using inversion recovery gradient echo 
      scanning (IR-GRE) sequence and MCLE. MCLE was compared to cine SSFP in the 
      assessment of wall motion, ejection fraction (EF), left ventricular (LV) mass, LV 
      end-diastolic volume (EDV), and to IR-GRE for measuring infarct size. RESULTS: 
      MCLE, IR-GRE, and SSFP imaging demonstrated excellent agreement in the assessment 
      of EF, LV infarct size, and LV mass (r > 0.95, P < 0.001 for all measures), as 
      well as in the assessment of wall motion (kappa statistic 0.75). CONCLUSION: MCLE 
      provided coregistered images for the assessment of viability and wall motion 
      without loss of accuracy in the assessment of quantitative cardiac parameters. 
      MCLE provides accurate quantitative cardiac assessment with reduced scan times 
      compared to the conventional sequences and thus may be used as an alternative to 
      conventional cine SSFP and IR-GRE imaging.
CI  - (c) 2009 Wiley-Liss, Inc.
FAU - Connelly, Kim A
AU  - Connelly KA
AD  - Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. 
      connellyk@smh.toronto.on.ca
FAU - Detsky, Jay S
AU  - Detsky JS
FAU - Graham, John J
AU  - Graham JJ
FAU - Paul, Gideon
AU  - Paul G
FAU - Vijayaragavan, Ram
AU  - Vijayaragavan R
FAU - Dick, Alexander J
AU  - Dick AJ
FAU - Wright, Graham A
AU  - Wright GA
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Magn Reson Imaging
JT  - Journal of magnetic resonance imaging : JMRI
JID - 9105850
RN  - 0 (Contrast Media)
RN  - K2I13DR72L (Gadolinium DTPA)
SB  - IM
MH  - Aged
MH  - Contrast Media
MH  - Female
MH  - *Gadolinium DTPA
MH  - Humans
MH  - Image Interpretation, Computer-Assisted
MH  - Magnetic Resonance Imaging, Cine/*methods
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*diagnosis
MH  - Reproducibility of Results
EDAT- 2009/09/30 06:00
MHDA- 2009/12/18 06:00
CRDT- 2009/09/30 06:00
PHST- 2009/09/30 06:00 [entrez]
PHST- 2009/09/30 06:00 [pubmed]
PHST- 2009/12/18 06:00 [medline]
AID - 10.1002/jmri.21907 [doi]
PST - ppublish
SO  - J Magn Reson Imaging. 2009 Oct;30(4):771-7. doi: 10.1002/jmri.21907.