PMID- 19800541
OWN - NLM
STAT- MEDLINE
DCOM- 20100104
LR  - 20161125
IS  - 1535-7732 (Electronic)
IS  - 1051-0443 (Linking)
VI  - 20
IP  - 10
DP  - 2009 Oct
TI  - Initial experience using N-butyl cyanoacrylate for embolization of lower 
      gastrointestinal hemorrhage.
PG  - 1312-9
LID - 10.1016/j.jvir.2009.06.031 [doi]
AB  - PURPOSE: To report initial experience using N-butyl cyanoacrylate (n-BCA) to 
      control lower gastrointestinal hemorrhage (LGIH). MATERIALS AND METHODS: From May 
      2005 to March 2009, 14 patients with LGIH underwent mesenteric angiography and 
      transcatheter arterial embolization using n-BCA. Candidacy was primarily based on 
      the patient's hemodynamic stability and the risk for future LGIH, determined by 
      the presence of at least one of the following risk factors: more than one 
      arterial feeder supplying the bleeding vessel, underlying coagulopathy, or need 
      to resume anticoagulation after embolization. Outcome measures included technical 
      success (immediate postembolic hemostasis confirmed with completion angiography 
      showing no further extravasation of contrast medium), clinical success 
      (postembolic hemostasis in the absence of complications 30 days after the 
      procedure), and clinical failure (recurrence of LGIH necessitating repeat 
      embolization or surgical treatment). RESULTS: Fourteen patients with active LGIH 
      were treated with n-BCA, with 100% technical success. Two patients had rebleeds 
      resulting in bowel resection. One patient experienced a minor rebleed that 
      spontaneously resolved. One patient died secondary to multiorgan failure in the 
      setting of multiple medical problems. The remaining 10 patients had complete 
      clinical success, experiencing no signs of rebleeding or infarction. CONCLUSIONS: 
      The results suggest that n-BCA can be a useful alternative embolic agent for the 
      treatment of hemodynamically unstable patients with LGIH when standard 
      microcoiling techniques fail or are not feasible and in patients with 
      coagulopathy.
FAU - Frodsham, Aaron
AU  - Frodsham A
AD  - Department of Radiology, Hospital of St Raphael, New Haven, CT 06511, USA. 
      aaron.frodsham@gmail.com
FAU - Berkmen, Turgut
AU  - Berkmen T
FAU - Ananian, Chris
AU  - Ananian C
FAU - Fung, Alice
AU  - Fung A
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PL  - United States
TA  - J Vasc Interv Radiol
JT  - Journal of vascular and interventional radiology : JVIR
JID - 9203369
RN  - 0 (Hemostatics)
RN  - F8CEP82QNP (Enbucrilate)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Embolization, Therapeutic/*methods
MH  - Enbucrilate/*therapeutic use
MH  - Female
MH  - Gastrointestinal Hemorrhage/*diagnostic imaging/*therapy
MH  - Hemostatics/*therapeutic use
MH  - Humans
MH  - Lower Gastrointestinal Tract/blood supply/diagnostic imaging
MH  - Male
MH  - Mesenteric Arteries/*diagnostic imaging
MH  - Middle Aged
MH  - Pilot Projects
MH  - Radiography, Interventional/methods
MH  - Treatment Outcome
EDAT- 2009/10/06 06:00
MHDA- 2010/01/05 06:00
CRDT- 2009/10/06 06:00
PHST- 2008/12/19 00:00 [received]
PHST- 2009/06/23 00:00 [revised]
PHST- 2009/06/29 00:00 [accepted]
PHST- 2009/10/06 06:00 [entrez]
PHST- 2009/10/06 06:00 [pubmed]
PHST- 2010/01/05 06:00 [medline]
AID - S1051-0443(09)00698-8 [pii]
AID - 10.1016/j.jvir.2009.06.031 [doi]
PST - ppublish
SO  - J Vasc Interv Radiol. 2009 Oct;20(10):1312-9. doi: 10.1016/j.jvir.2009.06.031.