PMID- 19801319
OWN - NLM
STAT- MEDLINE
DCOM- 20091012
LR  - 20101118
IS  - 1879-1190 (Electronic)
IS  - 1072-7515 (Linking)
VI  - 209
IP  - 4
DP  - 2009 Oct
TI  - Prognostic significance of intraoperatively estimated surgical stage in 
      curatively resected gastric cancer patients.
PG  - 461-7
LID - 10.1016/j.jamcollsurg.2009.06.001 [doi]
AB  - BACKGROUND: The aim of this study was to assess the prognostic significance of 
      intraoperatively estimated surgical stage (sStage) as a complementary role for 
      pathologic stage (pStage) in gastric cancer. STUDY DESIGN: This was a 
      retrospective study of 1,543 patients who underwent curative resection for 
      gastric cancer. Clinicopathologic and therapeutic factors, including sStage, were 
      analyzed for prognostic significance. Prognosis was stratified by sStage and 
      pStage, and the prognoses of patients with an overestimated sStage were compared 
      with those with a nonoverestimated sStage in the same pStage. RESULTS: Overall 
      accuracy of sStage versus pStage was 39% (T stage, 73.0%; N stage, 43.5%). 
      Survival curves were obviously stratified by sStage and pStage: Ia (97.5% versus 
      97.9%), Ib (94.3% versus 92.4%), II (89.6% versus 84.2%), IIIa (74.2% versus 
      69.3%), IIIb (54.4% versus 50.4%), and IV (55.6% versus 36.7%), respectively (p < 
      0.001). In addition to pStage, age and sStage were found to be significantly 
      associated with overall survival by univariate and multivariate analysis. In 
      pStages II, IIIa, and IIIb, intraoperatively overestimated patients had 
      significantly poorer survival than nonoverestimated patients. CONCLUSIONS: sStage 
      should be considered as a complementary prognostic factor for pStage in gastric 
      cancer after curative resection, especially in stages II and III patients.
FAU - Lee, Sang Eok
AU  - Lee SE
AD  - Department of Surgery, Konyang University Hospital, [corrected] Republic of 
      Korea.
FAU - Ryu, Keun Won
AU  - Ryu KW
FAU - Nam, Byung Ho
AU  - Nam BH
FAU - Lee, Jun Ho
AU  - Lee JH
FAU - Choi, Il Ju
AU  - Choi IJ
FAU - Kook, Myeong-Cherl
AU  - Kook MC
FAU - Park, Sook Ryun
AU  - Park SR
FAU - Kim, Young-Woo
AU  - Kim YW
LA  - eng
PT  - Journal Article
DEP - 20090808
PL  - United States
TA  - J Am Coll Surg
JT  - Journal of the American College of Surgeons
JID - 9431305
SB  - IM
EIN - J Am Coll Surg. 2010 Feb;210(2):260
MH  - Aged
MH  - Analysis of Variance
MH  - Antineoplastic Combined Chemotherapy Protocols/therapeutic use
MH  - Chemotherapy, Adjuvant
MH  - Female
MH  - Follow-Up Studies
MH  - *Gastrectomy/methods
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Lymphatic Metastasis
MH  - Male
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - Odds Ratio
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Stomach Neoplasms/drug therapy/mortality/*pathology/*surgery
EDAT- 2009/10/06 06:00
MHDA- 2009/10/13 06:00
CRDT- 2009/10/06 06:00
PHST- 2009/03/26 00:00 [received]
PHST- 2009/05/30 00:00 [revised]
PHST- 2009/06/02 00:00 [accepted]
PHST- 2009/10/06 06:00 [entrez]
PHST- 2009/10/06 06:00 [pubmed]
PHST- 2009/10/13 06:00 [medline]
AID - S1072-7515(09)00558-4 [pii]
AID - 10.1016/j.jamcollsurg.2009.06.001 [doi]
PST - ppublish
SO  - J Am Coll Surg. 2009 Oct;209(4):461-7. doi: 10.1016/j.jamcollsurg.2009.06.001. 
      Epub 2009 Aug 8.