PMID- 19803126
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20101005
LR  - 20161018
IS  - 1000-8713 (Print)
IS  - 1000-8713 (Linking)
VI  - 27
IP  - 3
DP  - 2009 May
TI  - [Simultaneous determination of 128 pesticide residues in milk by liquid 
      chromatography-tandem electrospray mass spectrometry].
PG  - 254-63
AB  - A method has been developed for the simultaneous determination of 128 pesticide 
      residues in milk by liquid chromatography-tandem electrospray mass spectrometry 
      (LC-ESI-MS/MS). A total of 10 mL milk was extracted with 20 mL acetonitrile (plus 
      4 g magnesium sulfate and 1 g NaCl) for two times. The concentrated supernatant 
      was cleaned-up by a C18 solid phase extraction cartridge to remove the lipophilic 
      compounds. The eluate was concentrated to about 0.5 mL in 45 degrees C water bath 
      with nitrogen. The 1 mL mixture of acetonitrile and water (3:2, v/v) was added 
      into the sample and mixed thoroughly for 30 s. The sample solution was filtered 
      by 0.2 microm millipore filters before LC-ESI-MS/MS determination. This method 
      was evaluated at the two spiked levels of 2 times and 8 times of limits of the 
      detection (LODs) in 5 parallel experiments, respectively. The results showed that 
      the average spiked recoveries of 128 pesticides at the low spiked level (0.14 
      microg/L-0.62 mg/L) were from 60.4% to 118.4% with relative standard deviations 
      (RSDs) of 2.1%-24.3%, and the average spiked recoveries at the high spiked level 
      (0.56 microg/L-2.48 mg/L) were from 64.4% to 118.5% with the RSDs of 1.3%-24.1%. 
      The method showed a good linear relationship with the correlation coefficients 
      over 0.99. The LODs were from 0.07 microg/L to 0.31 mg/L. This method is 
      selective, accurate and easy to operate.
FAU - Zheng, Junhong
AU  - Zheng J
AD  - College of Food Science and Engineering, Shandong Agricultural University, Taian 
      271018, China
FAU - Pang, Guofang
AU  - Pang G
FAU - Fan, Chunlin
AU  - Fan C
FAU - Wang, Minglin
AU  - Wang M
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
EDAT- 2009/10/07 06:00
MHDA- 2009/10/07 06:01
CRDT- 2009/10/07 06:00
PHST- 2009/10/07 06:00 [entrez]
PHST- 2009/10/07 06:00 [pubmed]
PHST- 2009/10/07 06:01 [medline]
PST - ppublish
SO  - Se Pu. 2009 May;27(3):254-63.