PMID- 19812862
OWN - NLM
STAT- MEDLINE
DCOM- 20100311
LR  - 20091008
IS  - 1995-9133 (Electronic)
IS  - 1684-1182 (Linking)
VI  - 42
IP  - 3
DP  - 2009 Jun
TI  - Serum immunoglobulin E levels in patients with primary hypogammaglobulinemia - 
      experience from a tertiary hospital in Taiwan.
PG  - 271-5
AB  - BACKGROUND AND PURPOSE: Primary hypogammaglobulinemia has been proposed to be 
      associated with an increased incidence of allergic diseases, but the correlation 
      between the clinical presentation and the serum immunoglobulin E (IgE) level has 
      not been studied in this patient group. This study investigated the correlation 
      of IgE levels and allergic condition in patients with primary 
      hypogammaglobulinemia. METHODS: Thirty five patients with primary 
      hypogammaglobulinemia were enrolled from September 2004 to March 2005. Serum IgE 
      levels were measured at clinic follow-up. Information regarding the patient's 
      history of allergic diseases, including atopic dermatitis, allergic rhinitis, 
      allergic conjunctivitis, and asthma, were collected from chart review and clinic 
      interviews. RESULTS: Significantly lower mean +/- standard deviation serum IgE 
      levels were found in allergic patients with primary hypogammaglobulinemia (123.9 
      +/- 148.8 IU/mL) than in the healthy control group (376.2 +/- 471.7 IU/mL) [p < 
      0.005] or in allergic patients without primary hypogammaglobulinemia (544.1 +/- 
      309.1 IU/mL) [p < 0.001]. CONCLUSIONS: Serum IgE level is not a suitable 
      diagnostic criterion or treatment guide for allergy in patients with primary 
      hypogammaglobulinemia.
FAU - Tsai, Wen-Ju
AU  - Tsai WJ
AD  - Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
FAU - Lin, Jeng-Yee
AU  - Lin JY
FAU - Yang, Yao-Hsu
AU  - Yang YH
FAU - Lee, Jyh-Hong
AU  - Lee JH
FAU - Chiang, Bor-Luen
AU  - Chiang BL
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Microbiol Immunol Infect
JT  - Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
JID - 100956211
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Agammaglobulinemia/*immunology
MH  - Child
MH  - Child, Preschool
MH  - Female
MH  - Hospitals
MH  - Humans
MH  - Hypersensitivity/*immunology
MH  - Immunoglobulin E/*blood
MH  - Male
MH  - Statistics, Nonparametric
MH  - Taiwan
MH  - Young Adult
EDAT- 2009/10/09 06:00
MHDA- 2010/03/12 06:00
CRDT- 2009/10/09 06:00
PHST- 2009/10/09 06:00 [entrez]
PHST- 2009/10/09 06:00 [pubmed]
PHST- 2010/03/12 06:00 [medline]
PST - ppublish
SO  - J Microbiol Immunol Infect. 2009 Jun;42(3):271-5.