PMID- 19816021 OWN - NLM STAT- MEDLINE DCOM- 20100202 LR - 20220330 IS - 1421-9883 (Electronic) IS - 0253-4886 (Linking) VI - 26 IP - 4 DP - 2009 TI - Laparoscopic Heller-Dor surgery for esophageal achalasia: impact of intraoperative real-time manometric feedback on postoperative outcomes. PG - 342-8 LID - 10.1159/000244512 [doi] AB - BACKGROUND: Laparoscopic Heller myotomy with Dor fundoplication (LHD) is one of the most established surgical procedures for esophageal achalasia. Preoperative esophageal manometry has been reported as useful to evaluate lower esophageal sphincter (LES) pressure. However, the feasibility, safety, and impact of its intraoperative use have not been fully evaluated, especially when enhanced with real-time 3-D pressure imaging. METHODS: LHD was attempted on 24 consecutive patients with esophageal achalasia. Manometry was performed at 3 time points during LHD: before myotomy, after myotomy, and after fundoplication. Investigations included esophagography, manometry, and 24-hour esophageal pH monitoring in the preoperative, short-term (0-5 months) and long-term (1-3 years) follow-up periods. RESULTS: The 3-D intraoperative manometric images were presented to the surgical crew on a monitor screen immediately after each measurement in all attempted cases (n = 13). Any residual high pressure zone of the LES was easily recognized and resolved with additional myotomy. Postoperative esophagographies showed resolution of esophageal dilatation. Manometric examination revealed significant reduction of LES pressure in the short-/long-term follow-up periods. PH monitoring showed no increase in acid reflux. Overall outcomes were satisfactory (symptom relief = 95%). CONCLUSION: Intraoperative manometry with real-time pressure feedback is a feasible, safe, and useful adjunct in LHD. CI - Copyright 2009 S. Karger AG, Basel. FAU - Endo, Shunji AU - Endo S AD - Department of Surgery, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan. FAU - Nakajima, Kiyokazu AU - Nakajima K FAU - Nishikawa, Kazuhiro AU - Nishikawa K FAU - Takahashi, Tsuyoshi AU - Takahashi T FAU - Souma, Yoshihito AU - Souma Y FAU - Taniguchi, Eiji AU - Taniguchi E FAU - Ito, Toshinori AU - Ito T FAU - Nishida, Toshirou AU - Nishida T LA - eng PT - Journal Article DEP - 20091006 PL - Switzerland TA - Dig Surg JT - Digestive surgery JID - 8501808 SB - IM MH - Adult MH - Esophageal Achalasia/*surgery MH - Esophagus/diagnostic imaging/*surgery MH - Feasibility Studies MH - Female MH - Follow-Up Studies MH - Fundoplication/methods MH - Humans MH - Laparoscopy/*methods MH - Male MH - Manometry/methods MH - Monitoring, Intraoperative/methods MH - Pneumoperitoneum, Artificial MH - Postoperative Complications/*prevention & control MH - Radiography EDAT- 2009/10/10 06:00 MHDA- 2010/02/03 06:00 CRDT- 2009/10/10 06:00 PHST- 2009/01/16 00:00 [received] PHST- 2009/06/07 00:00 [accepted] PHST- 2009/10/10 06:00 [entrez] PHST- 2009/10/10 06:00 [pubmed] PHST- 2010/02/03 06:00 [medline] AID - 000244512 [pii] AID - 10.1159/000244512 [doi] PST - ppublish SO - Dig Surg. 2009;26(4):342-8. doi: 10.1159/000244512. Epub 2009 Oct 6.