PMID- 19819074
OWN - NLM
STAT- MEDLINE
DCOM- 20100223
LR  - 20220316
IS  - 1872-6623 (Electronic)
IS  - 0304-3959 (Linking)
VI  - 147
IP  - 1-3
DP  - 2009 Dec 15
TI  - Contribution of the local and referred pain from active myofascial trigger points 
      in fibromyalgia syndrome.
PG  - 233-40
LID - 10.1016/j.pain.2009.09.019 [doi]
AB  - The generalized hypersensitivity associated with fibromyalgia syndrome (FMS) may 
      in part be driven by peripheral nociceptive sources. The aim of the study was to 
      investigate whether local and referred pain from active myofascial trigger points 
      (MTrPs) contributes to fibromyalgia pain. FMS patients and healthy controls (n=22 
      each, age- and gender-matched) were recruited. The surface area over the upper 
      trapezius muscle on each side was divided into 13 sub-areas (points) of 1cm in 
      diameter for each point. Pressure pain threshold (PPT) and the local and referred 
      pain pattern induced by manual palpation at 13 points bilaterally in the upper 
      trapezius were recorded. Results showed that PPT levels at all measured points 
      were significantly lower in FMS than controls. Multiple active MTrPs (7.4+/-2.2) 
      were identified bilaterally in the muscle in FMS patients, but no active MTrPs 
      were found in controls. The mid-fiber region of the muscle had the lowest PPT 
      level with the largest number of active MTrPs in FMS and with the largest number 
      of latent MTrPs in controls. The local and referred pain pattern induced from 
      active MTrPs bilaterally in the upper trapezius muscle were similar to the 
      ongoing pain pattern in the neck and shoulder region in FMS. In conclusion, 
      active MTrPs bilaterally in the upper trapezius muscle contribute to the neck and 
      shoulder pain in FMS. Active MTrPs may serve as one of the sources of noxious 
      input leading to the sensitization of spinal and supraspinal pain pathways in 
      FMS.
FAU - Ge, Hong-You
AU  - Ge HY
AD  - Laboratory for Musculoskeletal Pain and Motor Control, Center for Sensory-Motor 
      Interaction (SMI), Department of Health Science and Technology, Aalborg 
      University, Aalborg, Denmark. ghy@hst.aau.dk
FAU - Nie, Hongling
AU  - Nie H
FAU - Madeleine, Pascal
AU  - Madeleine P
FAU - Danneskiold-Samsoe, Bente
AU  - Danneskiold-Samsoe B
FAU - Graven-Nielsen, Thomas
AU  - Graven-Nielsen T
FAU - Arendt-Nielsen, Lars
AU  - Arendt-Nielsen L
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20091009
PL  - United States
TA  - Pain
JT  - Pain
JID - 7508686
SB  - IM
MH  - Aged
MH  - Analysis of Variance
MH  - Body Surface Area
MH  - Case-Control Studies
MH  - Electromyography
MH  - Female
MH  - Fibromyalgia/pathology/*physiopathology
MH  - Functional Laterality
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Muscle, Skeletal/pathology/physiopathology
MH  - Myofascial Pain Syndromes/*etiology/pathology
MH  - Pain Measurement/methods
MH  - Pain Threshold/*physiology
MH  - Pain, Referred/*complications/pathology
MH  - Physical Stimulation
MH  - Pressure/adverse effects
MH  - Reaction Time
EDAT- 2009/10/13 06:00
MHDA- 2010/02/24 06:00
CRDT- 2009/10/13 06:00
PHST- 2009/03/27 00:00 [received]
PHST- 2009/08/27 00:00 [revised]
PHST- 2009/09/17 00:00 [accepted]
PHST- 2009/10/13 06:00 [entrez]
PHST- 2009/10/13 06:00 [pubmed]
PHST- 2010/02/24 06:00 [medline]
AID - S0304-3959(09)00555-7 [pii]
AID - 10.1016/j.pain.2009.09.019 [doi]
PST - ppublish
SO  - Pain. 2009 Dec 15;147(1-3):233-40. doi: 10.1016/j.pain.2009.09.019. Epub 2009 Oct 
      9.