PMID- 19821225
OWN - NLM
STAT- MEDLINE
DCOM- 20100301
LR  - 20111117
IS  - 1439-4286 (Electronic)
IS  - 0018-5043 (Linking)
VI  - 42
IP  - 1
DP  - 2010 Jan
TI  - Influence of protein- versus carbohydrate-enriched feedings on physiological 
      responses during an ultraendurance climbing race.
PG  - 31-7
LID - 10.1055/s-0029-1237727 [doi]
AB  - This study investigated effects of a high protein (PROT) versus a high 
      carbohydrate (CHO) diet on performance and physiological responses during an 
      ultraendurance climbing race at moderate altitude. On two different periods, in a 
      randomised crossover design, ten climbers (30.0+/-0.9 years) participated in the 
      race (duration 29 h approximately, energy expenditure 43.6+/-1.2 MJ.day (-1)) and 
      were fed either with the PROT (30% protein content) or the CHO diet (68% 
      carbohydrate) each providing 16.74 MJ. Mental performance was assessed by the 
      Stroop test and we estimated maximal voluntary strength of quadriceps muscle. We 
      quantified metabolic and hormonal circulating concentrations. Mental performance 
      was unaffected after the two races, while muscular performance and body weight 
      were decreased (both p<0.01) with no diet effects. Decreases were measured for 
      IGF-I concentration and its binding protein IGFBP-3 (p<0.001), and increases for 
      cortisol and norepinephrine (p<0.01) with no diet effects. Glucose concentration 
      decreased (p<0.05) without diet effects, while amino acids (leucine, isoleucine, 
      valine, and tyrosine) decreased in CHO group (p<0.001). Leptin concentration 
      decreased (p<0.001) without diet effects, whereas total ghrelin increased in CHO 
      group (p<0.01). Our results showed that a high PROT or high CHO intake during 
      physical exertion at moderate altitude maintained mental performance, but did not 
      limit muscle force reduction and body weight loss. There was decreased glucose 
      availability, and hormonal responses indicated both catabolism and extreme energy 
      deficiency induced by exercise with opposite responses of ghrelin and leptin. The 
      ghrelin response was additionally indicative of macronutrient intake during the 
      race.
CI  - Georg Thieme Verlag KG Stuttgart New York.
FAU - Bourrilhon, C
AU  - Bourrilhon C
AD  - Department of Physiology, IMASSA, 91223 Bretigny-sur-Orge, France. 
      cbourrilhon@imassa.fr
FAU - Lepers, R
AU  - Lepers R
FAU - Philippe, M
AU  - Philippe M
FAU - Beers, P Van
AU  - Beers PV
FAU - Chennaoui, M
AU  - Chennaoui M
FAU - Drogou, C
AU  - Drogou C
FAU - Beauvieux, M C
AU  - Beauvieux MC
FAU - Burnat, P
AU  - Burnat P
FAU - Guezennec, C Y
AU  - Guezennec CY
FAU - Gomez-Merino, D
AU  - Gomez-Merino D
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20091009
PL  - Germany
TA  - Horm Metab Res
JT  - Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et 
      metabolisme
JID - 0177722
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Proteins)
RN  - 0 (Insulin)
RN  - 0 (Insulin-Like Growth Factor Binding Protein 3)
RN  - 67763-96-6 (Insulin-Like Growth Factor I)
SB  - IM
MH  - Adult
MH  - Altitude
MH  - Dietary Carbohydrates/administration & dosage/*metabolism
MH  - Dietary Proteins/administration & dosage/blood/*metabolism
MH  - Energy Metabolism
MH  - Humans
MH  - Insulin/blood
MH  - Insulin-Like Growth Factor Binding Protein 3/blood
MH  - Insulin-Like Growth Factor I/metabolism
MH  - Male
MH  - Mountaineering/*physiology
MH  - *Physical Endurance
EDAT- 2009/10/13 06:00
MHDA- 2010/03/02 06:00
CRDT- 2009/10/13 06:00
PHST- 2009/10/13 06:00 [entrez]
PHST- 2009/10/13 06:00 [pubmed]
PHST- 2010/03/02 06:00 [medline]
AID - 10.1055/s-0029-1237727 [doi]
PST - ppublish
SO  - Horm Metab Res. 2010 Jan;42(1):31-7. doi: 10.1055/s-0029-1237727. Epub 2009 Oct 
      9.