PMID- 19826829
OWN - NLM
STAT- MEDLINE
DCOM- 20100422
LR  - 20211020
IS  - 1434-4726 (Electronic)
IS  - 0937-4477 (Linking)
VI  - 267
IP  - 3
DP  - 2010 Mar
TI  - Narrow band imaging and high definition television in the assessment of laryngeal 
      cancer: a prospective study on 279 patients.
PG  - 409-14
LID - 10.1007/s00405-009-1121-6 [doi]
AB  - Narrow band imaging (NBI) is an optical technique in which a filtered light 
      reveals superficial carcinomas in view of their neoangiogenic pattern. The 
      accuracy of NBI is implemented by combining it with a high definition television 
      (HDTV) camera. The aim of this study was to prospectively evaluate the diagnostic 
      gain of NBI and HDTV in the assessment of laryngeal squamous cell carcinoma 
      (LSCC). Between April 2007 and December 2008, we analyzed by NBI with or without 
      HDTV 279 patients divided in two groups: Group A included 96 patients affected by 
      LSCC and Group B included 183 subjects under follow-up after treatment for the 
      same disease. Overall, 50 of 279 patients (18%) showed "suspicious" NBI findings 
      histologically confirmed as neoplastic. The sensitivity, specificity, accuracy, 
      positive and negative predictive rates of flexible NBI, HDTV with white light, 
      and HDTV with NBI in both groups confirmed the value of these two technologies. 
      In the pre- and intraoperative settings, NBI with or without HDTV provided better 
      definition of tumor staging and surgical margins. NBI has also a role in the 
      postoperative setting, due to its ability in early detection of persistences, 
      recurrences, and metachronous tumors.
FAU - Piazza, Cesare
AU  - Piazza C
AD  - Department of Otorhinolaryngology, Head and Neck Surgery, University of Brescia, 
      Piazza Spedali Civili 1, 25123 Brescia, Italy. ceceplaza@libero.it
FAU - Cocco, Daniela
AU  - Cocco D
FAU - De Benedetto, Luigi
AU  - De Benedetto L
FAU - Del Bon, Francesca
AU  - Del Bon F
FAU - Nicolai, Piero
AU  - Nicolai P
FAU - Peretti, Giorgio
AU  - Peretti G
LA  - eng
PT  - Journal Article
DEP - 20091014
PL  - Germany
TA  - Eur Arch Otorhinolaryngol
JT  - European archives of oto-rhino-laryngology : official journal of the European 
      Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the 
      German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
JID - 9002937
SB  - IM
MH  - Aged
MH  - Capillaries/pathology
MH  - Carcinoma, Squamous Cell/blood supply/*diagnosis/*pathology/surgery
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - *Image Enhancement
MH  - Laryngeal Neoplasms/blood supply/*diagnosis/*pathology/surgery
MH  - *Laryngoscopy
MH  - Male
MH  - Middle Aged
MH  - Neoplasm Staging
MH  - Neovascularization, Pathologic/*diagnosis/pathology/surgery
MH  - Prospective Studies
MH  - Sensitivity and Specificity
MH  - *Television
MH  - Video Recording/*instrumentation
MH  - Vocal Cords/blood supply/pathology
EDAT- 2009/10/15 06:00
MHDA- 2010/04/23 06:00
CRDT- 2009/10/15 06:00
PHST- 2009/04/20 00:00 [received]
PHST- 2009/09/17 00:00 [accepted]
PHST- 2009/10/15 06:00 [entrez]
PHST- 2009/10/15 06:00 [pubmed]
PHST- 2010/04/23 06:00 [medline]
AID - 10.1007/s00405-009-1121-6 [doi]
PST - ppublish
SO  - Eur Arch Otorhinolaryngol. 2010 Mar;267(3):409-14. doi: 
      10.1007/s00405-009-1121-6. Epub 2009 Oct 14.