PMID- 19854513
OWN - NLM
STAT- MEDLINE
DCOM- 20100114
LR  - 20190428
IS  - 1873-6750 (Electronic)
IS  - 0160-4120 (Linking)
VI  - 36
IP  - 1
DP  - 2010 Jan
TI  - Persistent organic pollutants in breast milk of mothers residing around an open 
      dumping site in Kolkata, India: specific dioxin-like PCB levels and fish as a 
      potential source.
PG  - 27-35
LID - S0160-4120(09)00201-3 [pii]
LID - 10.1016/j.envint.2009.09.003 [doi]
AB  - Concentrations of persistent organic pollutants (POPs) such as polychlorinated 
      dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), polychlorinated 
      biphenyls (PCBs) and organochlorine pesticides were measured in human breast milk 
      collected from mothers residing near an open dumping site and a reference site in 
      Kolkata, India during 2004-2005. POPs were detected in all the human milk samples 
      analyzed, suggesting that residents of Kolkata are widely exposed to these 
      contaminants. Concentrations of dioxin-like PCBs in the samples from the dumping 
      site were significantly higher than in the reference site samples, whereas no 
      such difference was found for PCDDs and PCDFs. In addition, significantly higher 
      concentrations of total PCBs were also observed in the samples from the dumping 
      site than the reference site. Interestingly, concentrations of total and 
      dioxin-like PCBs in the breast milk of mothers from the dumping site 
      significantly increased with the number of years of residence near the dumping 
      site. These results indicate that significant pollution sources of PCBs are 
      present in the dumping site of Kolkata and the residents living around are 
      exposed to relatively higher levels of PCBs. When the residue levels of dioxins 
      and related compounds in fish collected from ponds near the Kolkata dumping site 
      and the reference site were measured, it was found that dioxin-like PCB and TEQ 
      levels in fish from the dumping site were notably higher than those from the 
      reference site. This result indicates that fish is a potential source of PCBs for 
      residents living near the Kolkata dumping site.
FAU - Someya, Masayuki
AU  - Someya M
AD  - Center for Marine Environmental Studies (CMES), Ehime University, Bunkyo-cho 2-5, 
      Matsuyama 790-8577, Japan. Electronic address: somekiti@agr.ehime-u.ac.jp.
FAU - Ohtake, Masako
AU  - Ohtake M
AD  - Center for Marine Environmental Studies (CMES), Ehime University, Bunkyo-cho 2-5, 
      Matsuyama 790-8577, Japan.
FAU - Kunisue, Tatsuya
AU  - Kunisue T
AD  - Wadsworth Center, New York State Department of Health, School of Public Health, 
      State University of New York at Albany, Empire State Plaza, P.O. Box 509, Albany, 
      NY 12201-0509, USA; Department of Environmental Health Sciences, School of Public 
      Health, State University of New York at Albany, Empire State Plaza, P.O. Box 509, 
      Albany, NY 12201-0509, USA.
FAU - Subramanian, Annamalai
AU  - Subramanian A
AD  - Center for Marine Environmental Studies (CMES), Ehime University, Bunkyo-cho 2-5, 
      Matsuyama 790-8577, Japan.
FAU - Takahashi, Shin
AU  - Takahashi S
AD  - Center for Marine Environmental Studies (CMES), Ehime University, Bunkyo-cho 2-5, 
      Matsuyama 790-8577, Japan.
FAU - Chakraborty, Paromita
AU  - Chakraborty P
AD  - State Key Laboratory of Organic Geochemistry, Guangzhou Institute of 
      Geochemistry, The Chinese Academy of Sciences, PR China.
FAU - Ramachandran, Ramesh
AU  - Ramachandran R
AD  - Institute for ocean management Anna University, Chennai 600 025, India.
FAU - Tanabe, Shinsuke
AU  - Tanabe S
AD  - Center for Marine Environmental Studies (CMES), Ehime University, Bunkyo-cho 2-5, 
      Matsuyama 790-8577, Japan.
LA  - eng
PT  - Journal Article
DEP - 20091025
PL  - Netherlands
TA  - Environ Int
JT  - Environment international
JID - 7807270
RN  - 0 (Benzofurans)
RN  - 0 (Dibenzofurans, Polychlorinated)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticides)
RN  - 0 (Polychlorinated Dibenzodioxins)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Adult
MH  - Animals
MH  - Benzofurans/metabolism
MH  - Dibenzofurans, Polychlorinated
MH  - Environmental Monitoring
MH  - Environmental Pollutants/analysis/*metabolism
MH  - Female
MH  - Fishes/metabolism
MH  - Humans
MH  - Hydrocarbons, Chlorinated/*metabolism
MH  - India
MH  - *Maternal Exposure
MH  - Milk, Human/*metabolism
MH  - Pesticides/*metabolism
MH  - Polychlorinated Biphenyls/analysis/*metabolism
MH  - Polychlorinated Dibenzodioxins/analogs & derivatives/metabolism
MH  - Young Adult
EDAT- 2009/10/27 06:00
MHDA- 2010/01/15 06:00
CRDT- 2009/10/27 06:00
PHST- 2009/04/25 00:00 [received]
PHST- 2009/09/12 00:00 [revised]
PHST- 2009/09/15 00:00 [accepted]
PHST- 2009/10/27 06:00 [entrez]
PHST- 2009/10/27 06:00 [pubmed]
PHST- 2010/01/15 06:00 [medline]
AID - S0160-4120(09)00201-3 [pii]
AID - 10.1016/j.envint.2009.09.003 [doi]
PST - ppublish
SO  - Environ Int. 2010 Jan;36(1):27-35. doi: 10.1016/j.envint.2009.09.003. Epub 2009 
      Oct 25.