PMID- 19861396
OWN - NLM
STAT- MEDLINE
DCOM- 20100202
LR  - 20211020
IS  - 1532-2092 (Electronic)
IS  - 1099-5129 (Print)
IS  - 1099-5129 (Linking)
VI  - 11 Suppl 5
IP  - Suppl 5
DP  - 2009 Nov
TI  - Cardiac resynchronization therapy in heart failure patients with atrial 
      fibrillation.
PG  - v82-6
LID - 10.1093/europace/eup273 [doi]
AB  - Cardiac resynchronization therapy (CRT) is an important device-based, 
      non-pharmacological approach that has shown, in large randomized trials, to 
      improve left ventricular (LV) function and reduce both morbidity and mortality 
      rates in selected patients affected by advanced heart failure (HF): New York 
      Heart Association (NYHA) functional class III-IV, reduced LV systolic function 
      with an ejection fraction (EF) <or=35%, QRS duration >or=120 ms, on optimal 
      medical therapy, and who were in sinus rhythm. For the first time, the latest ESC 
      and AHA/ACC/HRS Guidelines have considered atrial fibrillation (AF) patients, who 
      constitute an important subgroup of HF patients, as eligible to receive CRT. 
      Nevertheless, these Guidelines did not include a strategy for defining 
      differentiated approaches according to AF duration or burden. In this review, the 
      authors explain in which way AF may interfere with adequate CRT delivery, how to 
      manage different AF burden, and finally present a brief overview on the effects 
      of CRT in AF patients.
FAU - Gasparini, Maurizio
AU  - Gasparini M
AD  - IRCCS Istituto Clinico Humanitas, Via Manzoni 56, Rozzano/Milano, Italy. 
      maurizio.gasparini@humanitas.it
FAU - Regoli, Francois
AU  - Regoli F
FAU - Galimberti, Paola
AU  - Galimberti P
FAU - Ceriotti, Carlo
AU  - Ceriotti C
FAU - Cappelleri, Alessio
AU  - Cappelleri A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Europace
JT  - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal 
      of the working groups on cardiac pacing, arrhythmias, and cardiac cellular 
      electrophysiology of the European Society of Cardiology
JID - 100883649
SB  - IM
MH  - Atrial Fibrillation/physiopathology/*therapy
MH  - Cardiac Pacing, Artificial/*methods
MH  - Catheter Ablation
MH  - Defibrillators
MH  - Heart Failure/physiopathology/*therapy
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Treatment Outcome
PMC - PMC2768583
EDAT- 2009/11/05 06:00
MHDA- 2010/02/03 06:00
PMCR- 2009/11/01
CRDT- 2009/10/29 06:00
PHST- 2009/10/29 06:00 [entrez]
PHST- 2009/11/05 06:00 [pubmed]
PHST- 2010/02/03 06:00 [medline]
PHST- 2009/11/01 00:00 [pmc-release]
AID - eup273 [pii]
AID - 10.1093/europace/eup273 [doi]
PST - ppublish
SO  - Europace. 2009 Nov;11 Suppl 5(Suppl 5):v82-6. doi: 10.1093/europace/eup273.