PMID- 19874253 OWN - NLM STAT- MEDLINE DCOM- 20100125 LR - 20181201 IS - 1744-7666 (Electronic) IS - 1465-6566 (Linking) VI - 10 IP - 16 DP - 2009 Nov TI - Vildagliptin in clinical practice: a review of literature. PG - 2745-57 LID - 10.1517/14656560903302265 [doi] AB - Vildagliptin is the second member of the DPP-IV inhibitor class of drugs licensed for the treatment of type 2 diabetes mellitus (T2DM). The novel action of these drugs has promoted a new outlook in the pathobiology of T2DM. This review undertakes to examine the clinical studies published to date, with the aim of evaluating the position of vildagliptin among the drugs that are now available to treat this common dysmetabolic state. FAU - Banerjee, Moulinath AU - Banerjee M AD - Central Manchester University Hospitals Foundation Trust, Department of Medicine, Manchester, M13 9WL, UK. FAU - Younis, Naveed AU - Younis N FAU - Soran, Handrean AU - Soran H LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PL - England TA - Expert Opin Pharmacother JT - Expert opinion on pharmacotherapy JID - 100897346 RN - 0 (Blood Glucose) RN - 0 (Dipeptidyl-Peptidase IV Inhibitors) RN - 0 (Nitriles) RN - 0 (Pyrrolidines) RN - I6B4B2U96P (Vildagliptin) RN - PJY633525U (Adamantane) SB - IM MH - Adamantane/*analogs & derivatives/pharmacokinetics/pharmacology/therapeutic use MH - Blood Glucose/analysis MH - Diabetes Mellitus, Type 2/drug therapy MH - Dipeptidyl-Peptidase IV Inhibitors/pharmacokinetics/pharmacology/*therapeutic use MH - Humans MH - Islets of Langerhans/drug effects MH - Nitriles/pharmacokinetics/pharmacology/*therapeutic use MH - Pyrrolidines/pharmacokinetics/pharmacology/*therapeutic use MH - Vildagliptin RF - 79 EDAT- 2009/10/31 06:00 MHDA- 2010/01/26 06:00 CRDT- 2009/10/31 06:00 PHST- 2009/10/31 06:00 [entrez] PHST- 2009/10/31 06:00 [pubmed] PHST- 2010/01/26 06:00 [medline] AID - 10.1517/14656560903302265 [doi] PST - ppublish SO - Expert Opin Pharmacother. 2009 Nov;10(16):2745-57. doi: 10.1517/14656560903302265.