PMID- 19877550
OWN - NLM
STAT- MEDLINE
DCOM- 20091201
LR  - 20190917
IS  - 0042-8450 (Print)
IS  - 0042-8450 (Linking)
VI  - 66
IP  - 9
DP  - 2009 Sep
TI  - Preoperative echocardiographic parameters influencing quality of life five years 
      after coronary artery bypass graft surgery.
PG  - 718-23
AB  - BACKGROUND/AIM: Factors associated with mortality and morbidity following 
      coronary artery bypass graft surgery have been well defined and the Parsonnet 
      score is widely used in mortality prediction. The evaluation of quality of life 
      has not been still implemented in everyday work and preoperative 
      echocardiographic factors affecting the quality of life in patients undergoing 
      coronary artery bypass graft surgery have been poorly documented. The aim of this 
      study was to evaluate echocardiographic parameters influencing quality of life 
      following coronary artery bypass graft surgery and its correlation with widely 
      used Parsonnet score. METHODS: A total of 449 consecutive patients with 
      myocardial revascularization, operated during 1999 and 2000 were enrolled in this 
      retrospective-prospective study. The patients with comorbidities were excluded as 
      well as those with in complete myocardial revascularization. A group of 180 
      patients who accepted to participate in quality of life evaluation was followed 
      for 60 months. The quality of life was evaluated using a questionnaire SF-36. 
      RESULTS: The mean patients' age was 57.8 +/- 7.8 years, 79.4% were males. A 
      5-year survival was 84.2%. The mean number of risk factors was 3.4 +/- 1.0. Most 
      of the patients were in New York Heart Association (NYHA) II class (104 of them 
      or 59.4%), 61 of them (34.9%) in NYHA III class and only 10 patients or 5.7% of 
      them were in NYHA IV class. The mean End-Diastolic Diameter (EDD) was 55.3 +/- 
      5.6 mm, mean End-Systolic Diameter (ESD) 38.7 +/- 5.6 mm and mean ejection 
      fraction (EF) 51.7 +/- 9.6%. Left atrium dilatation (p < 0.001), as well as left 
      ventricle dilatation (p < 0.001), low left ventricle ejection fraction (p < 
      0.001), multisegmental disorders of contractility (p < 0.001), and severe mitral 
      regurgitation (p < 0.001) were in negative correlation with almost all dimensions 
      of quality of life. ROC analysis showed that left ventricle EDD of 54.5 mm can be 
      used as good cut-off value for prediction of optimal quality of life, with 
      sensitivity of 57% and specificity of 70% (RR = 1.386), left ventricle ESD of 
      37.5 mm with sensitivity of 65% and specificity of 57% (RR = 0.855) and left 
      ventricle EF of 50% with sensitivity of 61% and specificity of 70% (RR = 0.916). 
      CONCLUSION: Echocardiographic parameters, that can easily be obtained 
      preoperatively, have strong predictive value not only in postoperative survival, 
      but also in determination of the quality of life of the patients five years after 
      coronary artery bypass graft surgery.
FAU - Zdravkovic, Marija
AU  - Zdravkovic M
AD  - Clinical Center "Bezanijska Kosa", Clinic for Cardiology, Belgrade, Serbia. 
      majadare@EUnet.yu
FAU - Ristic, Miljko
AU  - Ristic M
FAU - Milic, Natasa
AU  - Milic N
FAU - Zdravkovic, Darko
AU  - Zdravkovic D
FAU - Krotin, Mirjana
AU  - Krotin M
FAU - Randjelovic, Tomislav
AU  - Randjelovic T
LA  - eng
PT  - Journal Article
PL  - Serbia
TA  - Vojnosanit Pregl
JT  - Vojnosanitetski pregled
JID - 21530700R
SB  - IM
MH  - *Coronary Artery Bypass/mortality
MH  - *Echocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Contraction
MH  - Quality of Life
MH  - Surveys and Questionnaires
MH  - Ventricular Function
EDAT- 2009/11/03 06:00
MHDA- 2009/12/16 06:00
CRDT- 2009/11/03 06:00
PHST- 2009/11/03 06:00 [entrez]
PHST- 2009/11/03 06:00 [pubmed]
PHST- 2009/12/16 06:00 [medline]
AID - 10.2298/vsp0909718z [doi]
PST - ppublish
SO  - Vojnosanit Pregl. 2009 Sep;66(9):718-23. doi: 10.2298/vsp0909718z.