PMID- 19879825
OWN - NLM
STAT- MEDLINE
DCOM- 20100219
LR  - 20091127
IS  - 1875-0834 (Electronic)
IS  - 1760-2734 (Linking)
VI  - 11
IP  - 2
DP  - 2009 Dec
TI  - Evaluation of pacing site in dogs with naturally occurring complete heart block.
PG  - 79-88
LID - 10.1016/j.jvc.2009.06.002 [doi]
AB  - OBJECTIVE: To compare left ventricular synchronization and systolic performance 
      with transvenous pacing of the right ventricular apex (RVA), left ventricular 
      free wall (LVF) or simultaneous pacing of the RVA and LVF (BiV). ANIMALS, 
      MATERIALS AND METHODS: Seven canine patients with complete heart block. 
      Prospective study evaluating effect of pacing site. Twenty four hours following 
      implantation of transvenous BiV pacing systems, electrocardiograms and 
      echocardiograms were assessed during pacing from the: (1) Right Atrial 
      Appendage/RVA (RAA/RVA), (2) RAA/LVF, and (3) RAA/BiV. RESULTS: QRS duration was 
      significantly shorter with BiV pacing versus LVF pacing (p<0.001), or RVA pacing 
      (p<0.001). Echocardiographic indices of systolic performance fractional 
      shortening (FS), ejection fraction (EF), cardiac output (CO) were significantly 
      higher with BiV pacing than with pacing from the RVA (P=0.023, 0.006, and 0.002 
      respectively). Cardiac output, measured by the biplane Simpson's method, was 
      higher with LVF versus RVA pacing (P=0.036). There was no difference in FS or EF 
      when comparing LVF to RVA pacing. Tissue Doppler measurements of synchronization 
      and systolic performance did not show any difference between pacing mode, but a 
      significantly increased number of segments were seen to contract following aortic 
      valve closure during LVF pacing (P=0.0268) and RVA pacing (P=0.0197) as compared 
      to BiV pacing. CONCLUSIONS: Findings suggest that BiV pacing improves cardiac 
      output and systolic performance versus RVA pacing. This improvement however, is 
      not reflected in tissue Doppler indices of synchronization and systolic 
      performance.
FAU - Estrada, Amara H
AU  - Estrada AH
AD  - Department of Small Animal Clinical Sciences, College of Veterinary Medicine, 
      University of Florida, Gainesville, FL 32610, USA. estradaa@vetmed.ufl.edu
FAU - Maisenbacher, Herbert W 3rd
AU  - Maisenbacher HW 3rd
FAU - Prosek, Robert
AU  - Prosek R
FAU - Schold, Jesse
AU  - Schold J
FAU - Powell, Melanie
AU  - Powell M
FAU - VanGilder, James M
AU  - VanGilder JM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20091031
PL  - Netherlands
TA  - J Vet Cardiol
JT  - Journal of veterinary cardiology : the official journal of the European Society 
      of Veterinary Cardiology
JID - 101163270
SB  - IM
MH  - Animals
MH  - Dog Diseases/physiopathology/*therapy
MH  - Dogs
MH  - Electrocardiography/veterinary
MH  - Female
MH  - Heart Block/physiopathology/therapy/*veterinary
MH  - Heart Ventricles/physiopathology
MH  - Male
MH  - Pacemaker, Artificial/*veterinary
MH  - Prospective Studies
EDAT- 2009/11/03 06:00
MHDA- 2010/02/20 06:00
CRDT- 2009/11/03 06:00
PHST- 2009/03/09 00:00 [received]
PHST- 2009/05/17 00:00 [revised]
PHST- 2009/06/10 00:00 [accepted]
PHST- 2009/11/03 06:00 [entrez]
PHST- 2009/11/03 06:00 [pubmed]
PHST- 2010/02/20 06:00 [medline]
AID - S1760-2734(09)00059-9 [pii]
AID - 10.1016/j.jvc.2009.06.002 [doi]
PST - ppublish
SO  - J Vet Cardiol. 2009 Dec;11(2):79-88. doi: 10.1016/j.jvc.2009.06.002. Epub 2009 
      Oct 31.