PMID- 19895376
OWN - NLM
STAT- MEDLINE
DCOM- 20100519
LR  - 20091109
IS  - 1600-0897 (Electronic)
IS  - 1046-7408 (Linking)
VI  - 62
IP  - 6
DP  - 2009 Dec
TI  - Urgent termination of pregnancy in pre-eclampsia and panel of antiphospholipid 
      antibodies.
PG  - 412-7
LID - 10.1111/j.1600-0897.2009.00759.x [doi]
AB  - PROBLEM: The present work was undertaken to investigate the occurence of 
      autoantibodies to eight various phospholipids in time of urgent termination of 
      the pregnancy (sectio caesarea) in patients in reproductive age with severe 
      preeclamptic symptoms. METHOD OF STUDY: Autoantibodies against annexin V, 
      ph-serine, ph-ethanolamine, ph-inositol, ph-DL-glycerol, cardiolipin, 
      beta2-glycoprotein I (beta2-GPI), and phosphatidic acid were studied by ELISA 
      methods. RESULTS: Increased levels of IgA-beta2-glycoprotein I, 
      IgG-beta2-glycoprotein I, IgG- anti-ph-serine, and IgG-anticardiolipin were found 
      in sera of preeclamptic women in the time of urgent sectio caesarea when compared 
      to the control group with physiological pregnancy. CONCLUSION: Supposed increase 
      in various antiphospholipid antibodies (aPLs) levels due to the stress during the 
      short time of admission and a need for a quick medical decision to terminate the 
      pregnancy was not unambiguously proven, but our results are evidently influenced 
      by the current urgent life-saving treatment.
FAU - Hradecky, Libor
AU  - Hradecky L
AD  - Department of Gynecology and Obstetrics, Charles University and Faculty Hospital, 
      Pilsen, Czech Republic.
FAU - Subrt, Ivan
AU  - Subrt I
FAU - Ulcova-Gallova, Zdenka
AU  - Ulcova-Gallova Z
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Denmark
TA  - Am J Reprod Immunol
JT  - American journal of reproductive immunology (New York, N.Y. : 1989)
JID - 8912860
RN  - 0 (Antibodies, Antiphospholipid)
RN  - 0 (beta 2-Glycoprotein I)
RN  - 17885-08-4 (Phosphoserine)
SB  - IM
MH  - Abortion, Therapeutic
MH  - Adult
MH  - Antibodies, Antiphospholipid/*blood
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Female
MH  - Humans
MH  - Phosphoserine/*immunology
MH  - Placental Circulation/immunology
MH  - Pre-Eclampsia/blood/*immunology/physiopathology/therapy
MH  - Pregnancy
MH  - Thrombosis
MH  - beta 2-Glycoprotein I/*immunology
EDAT- 2009/11/10 06:00
MHDA- 2010/05/21 06:00
CRDT- 2009/11/10 06:00
PHST- 2009/11/10 06:00 [entrez]
PHST- 2009/11/10 06:00 [pubmed]
PHST- 2010/05/21 06:00 [medline]
AID - AJI759 [pii]
AID - 10.1111/j.1600-0897.2009.00759.x [doi]
PST - ppublish
SO  - Am J Reprod Immunol. 2009 Dec;62(6):412-7. doi: 10.1111/j.1600-0897.2009.00759.x.