PMID- 19905363 OWN - NLM STAT- MEDLINE DCOM- 20100113 LR - 20091112 IS - 1550-2376 (Electronic) IS - 1539-3755 (Linking) VI - 80 IP - 4 Pt 1 DP - 2009 Oct TI - Traffic by multiple species of molecular motors. PG - 041928 AB - We study the traffic of two types of molecular motors using the two-species asymmetric simple exclusion process (ASEP) with periodic boundary conditions and with attachment and detachment of particles. We determine characteristic properties such as motor densities and currents by simulations and analytical calculations. For motors with different unbinding probabilities, mean-field theory gives the correct bound density and total current of the motors, as shown by numerical simulations. For motors differing in their stepping probabilities, the particle-hole symmetry of the current-density relationship is broken and mean-field theory fails drastically. The total motor current exhibits exponential finite-size scaling, which we use to extrapolate the total current to the thermodynamic limit. Finally, we also study the motion of a single motor in the background of many nonmoving motors. FAU - Chai, Yan AU - Chai Y AD - Max Planck Institute of Colloids and Interfaces, Science Park Golm, 14424 Potsdam, Germany. FAU - Klumpp, Stefan AU - Klumpp S FAU - Muller, Melanie J I AU - Muller MJ FAU - Lipowsky, Reinhard AU - Lipowsky R LA - eng PT - Journal Article DEP - 20091028 PL - United States TA - Phys Rev E Stat Nonlin Soft Matter Phys JT - Physical review. E, Statistical, nonlinear, and soft matter physics JID - 101136452 RN - 0 (Molecular Motor Proteins) SB - IM MH - Biological Transport MH - Models, Biological MH - Molecular Motor Proteins/*metabolism MH - Probability EDAT- 2009/11/13 06:00 MHDA- 2010/01/14 06:00 CRDT- 2009/11/13 06:00 PHST- 2009/05/05 00:00 [received] PHST- 2009/08/14 00:00 [revised] PHST- 2009/11/13 06:00 [entrez] PHST- 2009/11/13 06:00 [pubmed] PHST- 2010/01/14 06:00 [medline] AID - 10.1103/PhysRevE.80.041928 [doi] PST - ppublish SO - Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Oct;80(4 Pt 1):041928. doi: 10.1103/PhysRevE.80.041928. Epub 2009 Oct 28.