PMID- 19908744
OWN - NLM
STAT- MEDLINE
DCOM- 20091211
LR  - 20190715
IS  - 1533-4880 (Print)
IS  - 1533-4880 (Linking)
VI  - 9
IP  - 12
DP  - 2009 Dec
TI  - Fabrication of nano scaled protein monolayer consisting of cytochrome c on 
      self-assembled 11-MUA layer for bioelectronic device.
PG  - 7136-40
AB  - The biomolecular/organic hetero-structure films (cytochrome 
      c/11-mercapto-undecanoic acid) on gold substrates were controlled and fabricated 
      with molecular level for developing valuable molecular electronic devices. 
      Cytochrome c is a metalloprotein having redox property, which can be directly 
      applicable to biomemory device as a active element. For efficient immobilization 
      of the protein on the gold substrate, 11-mercapto-undecanoic acid (11-MUA) was 
      used as a linker material between protein and inorganic substrate. The proposed 
      nano scaled biomolecular/organic hetero-structure layer (cytochrome c/11-MUA) on 
      gold surface was investigated by using surface plasmon resonance technique. The 
      molecular morphology of the fabricated protein layer was confirmed by scanning 
      tunneling microscopy. Electrochemical properties of fabricated 
      biomolecular/organic hetero layer were verified using cyclic voltammetry. Their 
      redox properties was sustained over 1000 cycles of cyclic voltametry. It proved 
      that the fabricated film was a suitable platform for the bioelectronic device 
      application.
FAU - Lee, Taek
AU  - Lee T
AD  - Department of Chemical and Biomolecular Engineering, Sogang University, #1 
      Shinsu-dong, Mapo-gu, Seoul 121-742, Republic of Korea.
FAU - Kim, Sang-Uk
AU  - Kim SU
FAU - Lee, Jin-Ho
AU  - Lee JH
FAU - Min, Junhong
AU  - Min J
FAU - Choi, Jeong-Woo
AU  - Choi JW
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Nanosci Nanotechnol
JT  - Journal of nanoscience and nanotechnology
JID - 101088195
RN  - 0 (11-mercaptoundecanoic acid)
RN  - 0 (Coated Materials, Biocompatible)
RN  - 0 (Fatty Acids)
RN  - 0 (Sulfhydryl Compounds)
RN  - 9007-43-6 (Cytochromes c)
SB  - IM
MH  - Biosensing Techniques/*instrumentation
MH  - Coated Materials, Biocompatible/chemistry
MH  - Crystallization/*methods
MH  - Cytochromes c/*chemistry
MH  - Electronics/*instrumentation
MH  - Equipment Design
MH  - Equipment Failure Analysis
MH  - Fatty Acids/*chemistry
MH  - Nanostructures/*chemistry/ultrastructure
MH  - Nanotechnology/instrumentation
MH  - Particle Size
MH  - Protein Binding
MH  - Sulfhydryl Compounds/*chemistry
MH  - Surface Plasmon Resonance/*instrumentation
EDAT- 2009/11/17 06:00
MHDA- 2009/12/16 06:00
CRDT- 2009/11/14 06:00
PHST- 2009/11/14 06:00 [entrez]
PHST- 2009/11/17 06:00 [pubmed]
PHST- 2009/12/16 06:00 [medline]
AID - 10.1166/jnn.2009.1663 [doi]
PST - ppublish
SO  - J Nanosci Nanotechnol. 2009 Dec;9(12):7136-40. doi: 10.1166/jnn.2009.1663.