PMID- 1992037 OWN - NLM STAT- MEDLINE DCOM- 19910312 LR - 20161123 IS - 0161-5505 (Print) IS - 0161-5505 (Linking) VI - 32 IP - 2 DP - 1991 Feb TI - Technetium-99m-methylene diphosphonate (MDP) uptake in a sympathetic effusion: an index of malignancy and a review of the literature. PG - 325-7 AB - We report a patient with a sympathetic pleural effusion secondary to T-cell lymphoma that accumulated the bone imaging agent, Technetium-99m-methylene diphosphonate (99mTc-MDP). This case is significant in that malignant cells were not present on three cytologic examinations of the pleural fluid or multiple pleural biopsies. We also present a review of the published literature on pleural effusions that accumulate bone tracers. We conclude that pleural effusions that accumulate 99mTc-MDP should be considered malignant or secondary to a malignancy and further work-up is essential even if the cytologic exam of the pleural fluid is unremarkable. FAU - Cole, T J AU - Cole TJ AD - Department of Radiology and Laboratory Services, Medical College of Virginia, Richmond. FAU - Balseiro, J AU - Balseiro J FAU - Lippman, H R AU - Lippman HR LA - eng PT - Case Reports PT - Journal Article PT - Review PL - United States TA - J Nucl Med JT - Journal of nuclear medicine : official publication, Society of Nuclear Medicine JID - 0217410 RN - X89XV46R07 (Technetium Tc 99m Medronate) SB - IM MH - Aged MH - Humans MH - Lymphoma, T-Cell/*complications MH - Male MH - Pleural Effusion, Malignant/diagnostic imaging/etiology/*metabolism MH - Radionuclide Imaging MH - Technetium Tc 99m Medronate/*pharmacokinetics RF - 7 EDAT- 1991/02/01 00:00 MHDA- 1991/02/01 00:01 CRDT- 1991/02/01 00:00 PHST- 1991/02/01 00:00 [pubmed] PHST- 1991/02/01 00:01 [medline] PHST- 1991/02/01 00:00 [entrez] PST - ppublish SO - J Nucl Med. 1991 Feb;32(2):325-7.